Bioavailability of quercetin from berries and the diet
Bioavailability of quercetin from berries and the diet
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DOI：
10.1207/s15327914nc5401_3
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发表时间：
2006-01-01
影响因子：
2.9
通讯作者：
Alfthan, Georg
中科院分区：
文献类型：
--
作者：
Erlund, Iris;Freese, Riitta;Alfthan, Georg
浆果富含各种多酚，包括类黄酮槲皮素。在这篇文章中，三个干预研究的结果调查从浆果槲皮素的生物利用度进行了审查。在第一项研究中，我们调查了食用黑加仑汁后槲皮素的短期动力学，结果表明槲皮素被迅速吸收。在第二项研究中，我们发现，在2个月的正常饮食中，每天食用100克越橘、黑加仑和越橘的受试者血浆槲皮素水平增加了50%。在第三项研究中，健康受试者食用蔬菜、浆果和其他水果含量高或低的饮食6周。在高蔬菜、浆果和其他水果摄入量的人群中，槲皮素浓度几乎翻了一番，而在这些食物摄入量低于正常水平的人群中，槲皮素浓度下降了30%。结果表明，血浆槲皮素可从含有浆果的饮食中生物利用，并表明它可能是一般水果和蔬菜摄入量的良好生物标志物。
Berries are a rich source of various polyphenols, including the flavonoid quercetin. In this article, the results of three intervention studies investigating the bioavailability of quercetin from berries are reviewed. In the first study, we investigated the short-term kinetics of quercetin after consumption of black currant juice and showed that quercetin is rapidly absorbed from it. In the second study, we showed that plasma quercetin levels increase up to 50% in subjects consuming 100 g/day of bilberries, black currants, and lingonberries as apart of their normal diets for 2 mo. In the third study, healthy subjects consumed a diet high or low in vegetables, berries, and other fruit for 6 wk. Quercetin concentrations nearly doubled in the high-vegetable, -berry, and -other fruit group and decreased by 30% in subjects consuming less of these foods than normally. The results showed that plasma quercetin is bioavailable from a diet containing berries and indicate that it may be a good biomarker of fruit and vegetable intake in general.