Papular Clear Cell Hyperplasia of the Eccrine Duct: A Precursor Lesion of Clear Cell Syringoma?

Papular Clear Cell Hyperplasia of the Eccrine Duct: A Precursor Lesion of Clear Cell Syringoma?
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小汗管丘疹性透明细胞增生:透明细胞汗管瘤的前兆病变?

DOI:
10.1097/dad.0000000000000339
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发表时间:
2015
期刊:
The American Journal of dermatopathology
影响因子:
--
通讯作者:
J. Rodríguez
J. Rodríguez
中科院分区:
--
文献类型:
--
作者:
M. Alonso;M. Cámara;M. Garrido;J. Rodríguez

文献摘要

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我们报告一位77岁的糖尿病患者,在切除鳞状细胞癌后,皮肤疤痕上出现无症状的丘疹。组织学检查发现一个明确的细胞增殖涉及分泌部分的外分泌腺。这种实体以前被命名为小汗腺导管的丘疹性透明细胞增生。这种透明细胞的变化可能是由糖尿病引起的糖原沉积引起的。我们推测丘疹状透明细胞增生可能是透明细胞胶质瘤的前驱病变。
We report the case of a 77-year-old diabetic patient with asymptomatic papular eruption developed over a cutaneous scar after the resection of a squamous cell carcinoma. Histological examination revealed a clear cell proliferation involving the secretory portion of the eccrine glands. This entity has been previously named as papular clear cell hyperplasia of the eccrine duct. This clear cell change might be caused by glycogen deposition because of diabetes. We postulate that papular clear cell hyperplasia could be a precursor lesion of clear cell syringoma.