Radiological outcome in rheumatoid arthritis is predicted by presence of antibodies against cyclic citrullinated peptide before and at disease onset, and by IgA-RF at disease onset

Radiological outcome in rheumatoid arthritis is predicted by presence of antibodies against cyclic citrullinated peptide before and at disease onset, and by IgA-RF at disease onset
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DOI:
10.1136/ard.2005.041376
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发表时间:
2006-04-01
影响因子:
27.4
通讯作者:
Rantapää-Dahlqvist, S
Rantapää-Dahlqvist, S
中科院分区:
医学1区
文献类型:
--
作者:
Berglin, E;Johansson, T;Rantapää-Dahlqvist, S

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目的:评估类风湿关节炎发病前和早期疾病(基线)时抗环瓜氨酸肽(抗CCP)和类风湿因子(RF)抗体对疾病活动和进展的意义。
Objective: To evaluate the significance of antibodies against cyclic citrullinated peptide (anti-CCP) and rheumatoid factors (RFs), before the onset of rheumatoid arthritis and when presenting as early disease (baseline), for disease activity and progression.Methods: 93 of a cohort of 138 patients with early rheumatoid arthritis (