A morphology-dependent bio-organic template for inorganic nanowire synthesis.
A morphology-dependent bio-organic template for inorganic nanowire synthesis.
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DOI：
10.1002/smll.201101014
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发表时间：
2011-07
期刊：
影响因子：
13.3
通讯作者：
Miao-Ping Chien;N. Gianneschi
中科院分区：
文献类型：
--
作者：
Miao-Ping Chien;N. Gianneschi
Biomolecular assemblies are attractive as templates in the hierarchical synthesis of 1D nanomaterials. Inherent to these templates are desirable properties including order at the nanometer length scale and well-defi ned patterns of selective recognition elements. [ 1–4 ] These advantages drive the interest in assemblies such as viruses [ 5–11 ] and microtubules [ 12 ] as the structural base for templating higherorder synthetic structure. Despite the potential for chemically and genetically modifying these structures, [ 13–18 ] a major inherent limitation is that one is largely restricted to natural building blocks including nucleic acids and amino acids. By contrast, purely synthetic unidimensional organic materials, [ 19–24 ] while chemically diverse, generally lack the programmable structural order of natural systems. Some exceptions include block copolymer 3D assemblies and 2D patterns, [ 25–31 ] as well as synthetic biomolecular hybrid materials having regular, predictable structural elements. [ 32–45 ] Herein, a wet chemical synthetic strategy [ 46–55 ] is presented for the directed assembly of inorganic nanoscale materials utilizing morphologically programmable DNA– block-copolymer micelle templates. We reasoned that with a method for selectively accessing various phases available to a micellar soft material in hand, one could plausibly facilitate the morphology-dependent, hierarchical assembly of higher-ordered materials. In a manner analogous to 2D template architectures generated by block copolymers, [ 25–31 ] our initial intention was to examine whether various morphologies of discrete amphiphilic block copolymer micelles programmed to assemble in a specifi c and switchable fashion via DNA-directed processes, [ 56 ] could be used to spatially organize inorganic nanoparticles (NPs). Therefore, the expectation was that Au NPs would bind to block copolymer micelles modifi ed with disulfi de ligands to give a variety of hybrid structures. Au NP binding has been observed previously utilizing templates consisting of ordered biological materials, for example, on viruses, [ 5–7 , 9–11 ]
