Nutritional Cognitive Neuroscience: Innovations for Healthy Brain Aging.
Nutritional Cognitive Neuroscience: Innovations for Healthy Brain Aging.
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DOI：
10.3389/fnins.2016.00240
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发表时间：
2016
影响因子：
4.3
通讯作者：
Barbey AK
中科院分区：
文献类型：
--
作者：
Zamroziewicz MK;Barbey AK
营养认知神经科学是一个新兴的跨学科研究领域，旨在了解营养在整个生命周期中对认知和大脑健康的影响。这一新兴领域的研究表明，营养的许多方面——从整个饮食到特定营养素——都会影响大脑的结构和功能，因此对理解健康大脑衰老的本质具有深远的意义。这篇重点综述的目的是研究营养认知神经科学的最新进展，重点是发现预测健康大脑衰老的营养生物标志物的方法。我们提出了一个综合框架，要求营养流行病学和认知神经科学研究的综合，包括：(i)基于营养生物标志物模式（nbp）分析的营养健康精确表征方法，以及（ii）来自高分辨率磁共振成像（MRI）的现代大脑健康指数。通过整合营养流行病学和认知神经科学的前沿技术，营养认知神经科学将继续推进我们对营养对衰老大脑的有益作用的理解，并建立有效的营养干预措施来促进健康的大脑衰老。
Nutritional cognitive neuroscience is an emerging interdisciplinary field of research that seeks to understand nutrition's impact on cognition and brain health across the life span. Research in this burgeoning field demonstrates that many aspects of nutrition—from entire diets to specific nutrients—affect brain structure and function, and therefore have profound implications for understanding the nature of healthy brain aging. The aim of this Focused Review is to examine recent advances in nutritional cognitive neuroscience, with an emphasis on methods that enable discovery of nutrient biomarkers that predict healthy brain aging. We propose an integrative framework that calls for the synthesis of research in nutritional epidemiology and cognitive neuroscience, incorporating: (i) methods for the precise characterization of nutritional health based on the analysis of nutrient biomarker patterns (NBPs), along with (ii) modern indices of brain health derived from high-resolution magnetic resonance imaging (MRI). By integrating cutting-edge techniques from nutritional epidemiology and cognitive neuroscience, nutritional cognitive neuroscience will continue to advance our understanding of the beneficial effects of nutrition on the aging brain and establish effective nutritional interventions to promote healthy brain aging.