SPONTANEOUS DISSECTIONS OF CERVICOCEPHALIC ARTERIES IN CHILDHOOD AND ADOLESCENCE

SPONTANEOUS DISSECTIONS OF CERVICOCEPHALIC ARTERIES IN CHILDHOOD AND ADOLESCENCE
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DOI:
10.1212/wnl.44.9.1607
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发表时间:
1994-09-01
期刊:
影响因子:
9.9
通讯作者:
PIEPGRAS, DG
PIEPGRAS, DG
中科院分区:
医学1区
文献类型:
--
作者:
SCHIEVINK, WI;MOKRI, B;PIEPGRAS, DG

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在梅奥诊所评估的263例自发性颈头动脉夹层患者中,18例(6.8%)年龄在18岁或以下(平均年龄12岁)。11例受累于颈动脉,7例受累于颅内动脉。在颅外,8例受累于颈内动脉,2例累及椎动脉,1例同时累及两条动脉。在颅内,只有前循环受到影响。所有患者都有脑或视网膜缺血症状,通常先于头痛。死亡病例为一名13岁男孩,他患有颅内动脉夹层和主动脉缩窄。其余17例患者的随访期为1~21年。11例颈动脉夹层患者中有10例临床恢复完全或良好,而7例颅内动脉夹层患者中仅4例临床恢复良好。2例颈动脉夹层患者和1例颅内动脉夹层患者复发动脉夹层。
Among 263 consecutive patients with spontaneous cervicocephalic arterial dissections evaluated at the Mayo Clinic, 18 (6.8%) were 18 years of age or younger (mean age, 12 years). The dissection involved the cervical arteries in 11 patients and the intracranial arteries in seven. Extracranially, the internal carotid artery was involved in eight patients, the vertebral artery in two, and both arteries in one. Intracranially, only the anterior circulation was affected. All the patients had cerebral or retinal ischemic symptoms, usually preceded by headache. Death occurred in a 13-year-old boy with intracranial arterial dissection and coarctation of the aorta. For the 17 remaining patients, the follow-up period ranged from 1 to 21 years. A complete or good clinical recovery occurred in 10 of the 11 patients with cervical arterial dissection but in only four of the seven with dissection of intracranial arteries. Recurrent arterial dissection occurred in two patients with cervical arterial dissections and in one patient with intracranial arterial dissection.