Ruthenium-Catalyzed Transformation of Aryl and Alkynyl Propargyl Ethers into Aryl and Alkynyl Ketones via Cleavage of a Carbon-Carbon Triple Bond
Ruthenium-Catalyzed Transformation of Aryl and Alkynyl Propargyl Ethers into Aryl and Alkynyl Ketones via Cleavage of a Carbon-Carbon Triple Bond
复制标题
钌催化碳-碳三键断裂将芳基和炔基丙炔醚转化为芳基和炔基酮
DOI：
10.1021/om049711m
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发表时间：
2004
期刊：
影响因子：
2.8
通讯作者：
Rai‐Shung Liu
中科院分区：
文献类型：
--
作者：
Hung;Haw;Yu;Rai‐Shung Liu
用水和TpRuPPh3(CH3CN)2PF6催化剂在热二氯乙烷中处理芳基和炔基丙炔醚，使丙炔醚基团脱除，得到芳基和炔基酮。对反应溶液上方的气体混合物的分析表明，存在一氧化碳、乙烯、乙烷和一氧化碳，它们是由丙炔醚官能与水的降解产生的。根据反应产物，提出了合理的反应机理。该催化反应是由丙炔醚衍生物制备芳基酮和炔基酮的可靠方法。
Treatment of aryl and alkynyl propargyl ethers with water and TpRuPPh3(CH3CN)2PF6 catalyst in hot dichloroethane led to the removal of the propargyl ether group and gave aryl and alkynyl ketones efficiently. Analysis of the gaseous mixture above the reaction solution showed the presence of carbon monoxide, ethylene, ethane, and carbon monoxide, produced from degradation of the propargyl ether functionality with water. A plausible reaction mechanism is proposed on the basis of reaction products. This catalytic reaction proves to be a reliable method to obtain aryl and alkynyl ketones from their propargyl ether derivatives.