Assessment of depression prevalence in rural Uganda using symptom and function criteria
Assessment of depression prevalence in rural Uganda using symptom and function criteria
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DOI：
10.1007/s00127-004-0763-3
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发表时间：
2004-06-01
影响因子：
4.4
通讯作者：
Ndogoni, L
中科院分区：
文献类型：
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作者：
Bolton, P;Wilk, CM;Ndogoni, L
背景：我们试图评估受HIV严重影响的撒哈拉以南非洲地区重度抑郁症的患病率，使用当地验证的仪器测量症状和功能标准。方法采用加权系统随机抽样法，对乌干达西南部马萨卡和拉凯地区的600户家庭进行抽样调查。采用霍普金斯症状检查表（DHSCL）抑郁部分的本地验证版本和社区生成的功能障碍指数对587名受访者进行了访谈。结果21%的受访者根据DSM-IV五项标准中的三项（包括功能障碍）被诊断为抑郁症，而仅使用症状标准的比例为24.4%。年龄增加和受教育程度降低与患抑郁症的风险增加有关；然而，没有发现性别影响。结论：在撒哈拉以南非洲，大多数基于DSM-IV的基于社区的抑郁症评估仅使用症状标准。我们发现扩展标准以更接近完整的DSM-IV是可行的，从而使更准确的患病率评估成为可能。这种方法表明，重度抑郁症和相关的功能障碍是这一人群的一个实质性问题。
Background We sought to assess the prevalence of major depression in a region of sub-Saharan Africa severely affected by HIV, using symptom and functional criteria as measured with locally validated instruments. Method Six hundred homes in the Masaka and Rakai districts of southwest Uganda were selected by weighted systematic random sampling. A locally validated version of the depression section of the Hopkins Symptom Check List (DHSCL) and a community-generated index of functional impairment were used to interview 587 respondents. Results Of respondents, 21% were diagnosed with depression using three of the five DSM-IV criteria (including function impairment) compared with 24.4% using symptom criteria alone. Increased age and lower educational levels are associated with a greater risk for depression; however, a gender effect was not detected. Conclusions Most community-based assessments of depression in sub-Saharan Africa based on the DSM-IV have used symptom criteria only.We found that expanding criteria to more closely match the complete DSM-IV is feasible, thereby making more accurate assessments of prevalence possible. This approach suggests that major depression and associated functional impairment are a substantial problem in this population.