Validation of GEANT4, an object-oriented Monte Carlo toolkit, for simulations in medical physics
Validation of GEANT4, an object-oriented Monte Carlo toolkit, for simulations in medical physics
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DOI：
10.1118/1.1644532
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发表时间：
2004-03-01
期刊：
影响因子：
3.8
通讯作者：
Roy, R
中科院分区：
文献类型：
--
作者：
Carrier, JF;Archambault, L;Roy, R
GEANT4（几何和跟踪4）是一个面向对象的蒙特卡罗模拟工具包，由世界各地的科学家合作开发。它模拟了粒子穿过物质的过程。为了验证GEANT4在医学物理中的应用，进行了不同的仿真。结果与基于医学物理学中广泛使用的三种蒙特卡罗代码（MCNP、EGS4和EGSnrc）的已发表结果进行了比较。在可能的情况下，还将仿真结果与实验数据进行了比较。测试了不同的几何形状（多层和均匀的幻影），考虑了不同的光源（点源和宽平行光束），并模拟了不同能量的不同初级粒子（光子和电子）。对于异质介质，蒙特卡罗码之间存在显著差异，相对差异可达5%以上。对于均匀介质中的单能电子，GEANT4与实验测量值的差异与EGSnrc与实验测量值的差异相似；对于深度-剂量曲线，用峰值剂量的分数表示的差值总是小于4%。我们得出结论，GEANT4是一个有前途的蒙特卡罗模拟工具包，用于低能耗医疗应用。(C) 2004年美国医学物理学家协会。
GEANT4 (GEometry ANd Tracking 4) is an object-oriented Monte Carlo simulation toolkit that has been developed by a worldwide collaboration of scientists. It simulates the passage of particles through matter. In order to validate GEANT4 for medical physics applications, different simulations are conducted. The results are compared to published results based on three Monte Carlo codes widely used in medical physics: MCNP, EGS4, and EGSnrc. When possible, the simulation results are also compared to experimental data. Different geometries are tested (multilayer and homogeneous phantoms), different sources considered (point-source and broad parallel beam), and different primary particles simulated (photons and electrons) at different energies. For the heterogeneous media, there are notable differences between the Monte Carlo codes reaching up to over 5% in relative difference. For the monoenergetic electrons in a homogeneous medium, the difference between GEANT4 and the experimental measurements is similar to the difference between EGSnrc and the experimental measurements; for the depth-dose curves, the difference expressed as a fraction of the peak dose is always smaller than 4%. We conclude that GEANT4 is a promising Monte Carlo simulation toolkit for low-energy medical applications. (C) 2004 American Association of Physicists in Medicine.