Blood pressure responses to lifestyle physical activity among young, hypertension-prone African-American women.
Blood pressure responses to lifestyle physical activity among young, hypertension-prone African-American women.
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年轻、易患高血压的非洲裔美国女性的血压对生活方式体育活动的反应。
DOI：
10.1097/00005082-200703000-00007
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Hollenberg,StevenM
中科院分区：
文献类型：
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作者：
Staffileno,BethA;Minnick,Ann;Coke,LolaA;Hollenberg,StevenM
背景：缺乏体育锻炼和肥胖会增加高血压的风险，而且两者在非洲裔美国女性中的发病率都高于白人女性。有规律的身体活动是降低心血管风险的重要干预措施，但满足年轻久坐的非洲裔美国妇女需求的理想身体活动状况仍不清楚。我们进行了一项随机、平行、单盲的研究，以检查生活方式体力活动（LPA）对18至45岁患有高血压前期或未经治疗的1期高血压的久坐不动的非洲裔美国女性血压指数的影响。主要的干预措施是一个为期8周的个性化的，以家庭为基础的计划，其中随机分配到运动组的妇女（n= 14）被指示从事与生活方式相容的体力活动（例如，步行、爬楼梯）10分钟，每天3次，每周5天，以对应于50%至60%心率储备强度的规定心率。不运动组（n= 10）的女性继续进行日常活动。袖带、动态和压力负荷指数的平均变化采用配对t检验进行比较，体力活动坚持率以百分比表示。036），舒张压状态降低到高血压前水平（90.8 vs 87.4 mm Hg），夜间压力负荷降低幅度大于不运动组。LPA的依从性在所有指标上都非常高（65%-98%），并且与收缩压的变化相关（r=-0.620，P=.结论：LPA的蓄积降低了袖带负荷、步行负荷和压力负荷。LPA的积累似乎耐受性良好，在这个样本的年轻非洲裔美国妇女的可行性，证明了整体的高依从率。考虑到非裔美国人压力相关临床后遗症的过度负担以及压力负荷与靶器官损伤之间的强相关性，LPA可能是该人群中实用且有效的策略。
Background:Physical inactivity and obesity increase the risk for hypertension, and both are more prevalent in African-American than Caucasian women. Regular physical activity serves as an important intervention for reducing cardiovascular risk, yet the ideal physical activity profile to meet the needs of young, sedentary African-American women remains unclear. We performed a randomized, parallel, single-blind study to examine the effect of lifestyle physical activity (LPA) on blood pressure indices in sedentary African-American women aged 18 to 45 years with prehypertension or untreated stage 1 hypertension.Methods:The primary intervention was an 8-week individualized, home-based program in which women randomized to Exercise (n= 14) were instructed to engage in lifestyle-compatible physical activity (eg, walking, stair climbing) for 10 minutes, 3 times a day, 5 days a week, at a prescribed heart rate corresponding to an intensity of 50% to 60% heart rate reserve. Women in the No Exercise group (n= 10) continued with their usual daily activities. Mean changes in cuff, ambulatory, and pressure load indices were compared using paired t tests, and physical activity adherence was expressed as percentages.Results:Women in the Exercise group had a significant reduction in systolic blood pressure (− 6.4 mm Hg, P=. 036), a decrease in diastolic blood pressure status to the prehypertensive level (90.8 vs 87.4 mm Hg), and greater reductions in nighttime pressure load compared with the No Exercise group. Adherence to LPA was exceedingly high by all measures (65%-98%) and correlated with change in systolic blood pressure (r=− 0.620, P=. 024).Conclusion:The accumulation of LPA reduced cuff, ambulatory, and pressure load. The accumulation of LPA appears well tolerated and feasible in this sample of young African-American women, demonstrated by the overall high adherence rates. Given the excess burden of pressure-related clinical sequelae among African Americans and the strong correlation between pressure load and target organ damage, LPA may represent a practical and effective strategy in this population.