OCCUPATIONAL ASTHMA DUE TO PEPSIN

OCCUPATIONAL ASTHMA DUE TO PEPSIN
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DOI:
10.1016/0091-6749(84)90513-x
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发表时间:
1984-01-01
影响因子:
14.2
通讯作者:
DOLOVICH, J
DOLOVICH, J
中科院分区:
医学1区
文献类型:
--
作者:
CARTIER, A;MALO, JL;DOLOVICH, J

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A 30 yr old atopic worker exposed to pepsin powder, herb and pollen extracts at work developed an increase in asthmatic symptoms. Monitoring of peak expiratory flow rate revealed more important fluctuations at work. Skin prick tests yielded a large immediate reaction to pepsin. Specific inhalation challenges confirmed the diagnosis; an intense early response was documented after exposure to pepsin. The pepsin IgE RAST [radioallergosorbent test] was positive and selectively inhibited by pepsin.