THE MOTOR OUTPUT OF THE MAUTHNER CELL, A RETICULOSPINAL COMMAND NEURON
THE MOTOR OUTPUT OF THE MAUTHNER CELL, A RETICULOSPINAL COMMAND NEURON
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DOI：
10.1016/0006-8993(90)91012-6
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发表时间：
1990-05-28
期刊：
影响因子：
2.9
通讯作者：
DIDOMENICO, R
中科院分区：
文献类型：
--
作者：
NISSANOV, J;EATON, RC;DIDOMENICO, R
我们电刺激个别Mauthner（M-）细胞，以确定其运动的C-启动游泳金鱼的贡献。与感觉诱发的C-启动相比，由单个M细胞的电刺激触发的M-反射明显较弱且变化较小。与感觉诱发的C-起始相比，第1阶段的M-反射在持续时间和角度上都较长。这转化为在阶段1期间角速度平均降低22%。同样，在第2阶段，鱼移动的距离减少了15%，第2阶段的转向角的绝对值减少了47%。此外，第1和第2阶段之间的正常机械或神经耦合似乎因M反射而改变。从这个和我们最近的其他研究中，我们得出结论，必须有两个主要的网状脊髓神经元的逃逸触发网络。第一组包括M单元，并确定响应的初始左右方向和阶段1角度的范围。从以前的EMG记录中，我们知道第二组神经元可以在第1阶段细胞后5-15 ms（平均9 ms）内放电。这些决定了第二阶段的开始时间和方向。两个主组的耦合一起导致C-启动的全推进力和转向灵活性。
We electrically stimulated individual Mauthner (M-) cells to determine their motor contribution to C-starts of swimming goldfish. In comparison with sensory-evoked C-starts, M-reflexes triggered by electrical stimulation of single M-cells were significantly weaker and less variable. Stage 1 turns were both longer in duration and smaller in angle for the m-reflex when compared with the sensory-evoked C-start. This translates to an average reduction of 22% in angular velocity during stage 1. Likewise, during stage 2, the distance moved by the fish was reduced by 15% and the absolute value of stage 2 turning angle was reduced by 47%. In addition, the normal mechanical or neural coupling between stages 1 and 2 appeared to be altered for the M-reflex. From this and our other recent studies, we conclude that there must be two primary groups of reticulospinal neurons in the escape triggering network. The first group includes the M-cell and determines the initial left-right direction of the response and the extent of stage 1 angle. From previous EMG recordings we know that the second group of neurons can fire within 5-15 ms (average, 9 ms) after the stage 1 cells. These determine the onset time and direction of stage 2. Together the coupling of the two primary groups results in the full propulsive force and turning flexibility of the C-start.