Fibroblast mechanics in three-dimensional collagen matrices
Fibroblast mechanics in three-dimensional collagen matrices
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DOI：
10.1016/j.jbmt.2008.03.005
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发表时间：
2008-07-01
影响因子：
1.4
通讯作者：
Grinnell, Frederick
中科院分区：
文献类型：
--
作者：
Grinnell, Frederick
筋膜为身体的其他组织提供机械支撑和框架。1型胶原是筋膜的主要蛋白质成分，成纤维细胞是主要负责其生物合成和重塑的细胞类型。成纤维细胞与胶原基质相互作用的研究提供了关于细胞-基质张力状态和生长因子特异性如何调节细胞迁移和基质重塑的新见解。(C)2008爱思唯尔有限公司保留所有权利。
Fascia provides mechanical support and frameworks for the other tissues of the body. Type 1 collagen is the major protein component of fascia, and fibroblasts are the cell type primarily responsible for its biosynthesis and remodeling. Research on fibroblasts interacting with collagen matrices provides new insights regarding how cell-matrix tension state and growth factor specificity regulate cell migration and matrix remodeling. (C) 2008 Elsevier Ltd. All rights reserved.