Cutaneous manifestations of anthrax in Eastern Anatolia: a review of 39 cases.
Cutaneous manifestations of anthrax in Eastern Anatolia: a review of 39 cases.
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安纳托利亚东部炭疽病的皮肤表现：39 例病例回顾。
DOI：
10.18926/amo/32827
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发表时间：
2003
影响因子：
0.5
通讯作者：
P. Demiröz
中科院分区：
文献类型：
--
作者：
H. Irmak;T. Buzgan;M. Karahocagil;Nurten Sakarya;H. Akdeniz;H. Çaksen;P. Demiröz
炭疽病本质上是一种食草动物的疾病。最常见的疾病是皮肤炭疽，占所有病例的 95%。我们在此报告了 6 年来在安纳托利亚东部发现的 39 例人类皮肤炭疽病例。临床表现为恶性水肿16例（41%），恶性脓疱23例（59%）。 13名患者（33.3%）病灶附近存在继发细菌感染。使用革兰氏染色涂片在 25 名患者（64%）中观察到该药剂，并从 15 名患者（38.5%）中分离出炭疽杆菌。除一名青霉素过敏的患者外，所有患者均接受青霉素 G 或青霉素普鲁卡因治疗。一名颈部水肿患者（2.5%）因喉部水肿和败血症综合征死亡。总之，我们发现皮肤炭疽的皮损外观可能会有所不同，这一事实，加上这种疾病的罕见性，导致医务人员普遍缺乏经验，可能会使非农业环境中的诊断变得困难
Anthrax is essentially a disease of grazing herbivorous animals. The most common form of the disease is cutaneous anthrax, which accounts for 95% of all cases. We report here 39 cutaneous anthrax cases in humans that were seen in Eastern Anatolia over a six-year period. The clinical presentation was malignant edema in 16 of the cases (41%) and malignant pustule in 23 (59%). A secondary bacterial infection was present in 13 patients (33.3%) in the vicinity of the lesions. The agent was observed using Gram-stained smears in 25 patients (64%), and Bacillus anthracis was isolated from 15 patients (38.5%). All of the patients were treated with penicillin G or penicillin procaine, except one patient who had a penicillin allergy. One patient with cervical edema (2.5%) died as a result of laryngeal edema and sepsis syndrome. In conclusion, we found that the appearance of the skin lesion of cutaneous anthrax may vary, and this fact, combined with the rarity of this disease, which contributes to a general lack of experience among medical personnel, may make diagnosis difficult in nonagricultural settings