Translocation of soft phytoglycogen nanoparticles through solid-state nanochannels
Translocation of soft phytoglycogen nanoparticles through solid-state nanochannels
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DOI：
10.1039/c9tb01048c
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发表时间：
2019-11-07
影响因子：
7
通讯作者：
Hore, Michael J. A.
中科院分区：
文献类型：
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作者：
Lenart, William R.;Kong, Weiwei;Hore, Michael J. A.
植物糖原纳米颗粒是柔软的，天然衍生的纳米材料，具有高度均匀的尺寸，接近35纳米。它们的内部由一个高度分枝的多糖核心组成，其中含有超过其干质量200%的水。在这项工作中，我们通过观察它们在阻塞直径在60到100纳米之间的固态纳米通道时产生的阻断事件来测量植物糖原颗粒的易位。易位信号是用泊松-能-普朗克计算来解释的，其“硬度参数”描述了溶剂可以穿透粒子内部的程度。我们发现理论和实验在定量上是一致的，这使我们能够在每个粒子的基础上提取粒子的物理特性。
Phytoglycogen nanoparticles are soft, naturally-derived nanomaterials with a highly uniform size near 35 nm. Their interior is composed of a highly-branched polysaccharide core that contains more than 200% of its dry mass in water. In this work, we measure the translocation of phytoglycogen particles by observing blockade events they create when occluding solid-state nanochannels with diameters between 60 and 100 nm. The translocation signals are interpreted using Poisson-Nernst-Planck calculations with a "hardness parameter" that describes the extent to which solvent can penetrate through the interior of the particles. Theory and experiment were found to be in quantitative agreement, allowing us to extract physical characteristics of the particles on a per particle basis.