Role of cytokine polymorphisms in the risk of distal gastric cancer development
Role of cytokine polymorphisms in the risk of distal gastric cancer development
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DOI：
10.1158/1055-9965.epi-04-0889
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发表时间：
2005-08-01
影响因子：
3.8
通讯作者：
Olivares, AZ
中科院分区：
文献类型：
--
作者：
Perez, GIP;Garza-Gonzalez, E;Olivares, AZ
本文就细胞因子多态性在不同人群中的作用及其与远端胃癌发生的关系作一综述。我们包括了幽门螺杆菌定植的人群以及没有定植的人群。我们发现，单靠多态性的研究似乎不足以评估胃癌的风险，有必要沿着研究H. pylori菌株，以更好地确定与远端胃癌相关的危险因素。
We review the current information concerning the role of cytokine polymorphisms and the risk of develop distal gastric cancer in different populations. We have included populations colonized with Helicobacter pylori as well as populations without colonization. We found that the study of polymorphisms alone seems insufficient to assess gastric cancer risk and it is necessary to examine environmental factors in different ethnic groups and geographic areas along with the study of H. pylori strains to define better the risk factors associated with distal gastric cancer.