The spectro-contextual encoding and retrieval theory of episodic memory.
The spectro-contextual encoding and retrieval theory of episodic memory.
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DOI：
10.3389/fnhum.2014.00075
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发表时间：
2014
影响因子：
2.9
通讯作者：
Ekstrom AD
中科院分区：
文献类型：
--
作者：
Watrous AJ;Ekstrom AD
频谱指纹假说假定不同频率的振荡是不同认知操作的基础，它为大脑区域之间的相互作用如何支持感知和注意过程提供了一种解释。在此，我们探索并将这一观点扩展到人类情景记忆的编码和提取领域。结合从突触到认知组织水平的研究结果，我们认为频谱精确的交叉频率耦合和相位同步促进了海马体-新皮层细胞组装的形成，形成了情景记忆的基础。我们认为，细胞集合放电模式以及海马-新皮层网络内大脑振荡活动的整体模式都代表了特定记忆的内容。根据情境恢复和多重痕迹理论的观点，我们认为记忆检索是由内部和/或外部因素驱动的，这些因素在情景编码过程中重现了这些频率特定的振荡模式。这些想法被综合成一种新的情景记忆模型（光谱-上下文编码和检索理论，简称SCERT），为未来的研究提供了几个可测试的预测。
The spectral fingerprint hypothesis, which posits that different frequencies of oscillations underlie different cognitive operations, provides one account for how interactions between brain regions support perceptual and attentive processes. Here, we explore and extend this idea to the domain of human episodic memory encoding and retrieval. Incorporating findings from the synaptic to cognitive levels of organization, we argue that spectrally precise cross-frequency coupling and phase-synchronization promote the formation of hippocampal-neocortical cell assemblies that form the basis for episodic memory. We suggest that both cell assembly firing patterns as well as the global pattern of brain oscillatory activity within hippocampal-neocortical networks represents the contents of a particular memory. Drawing upon the ideas of context reinstatement and multiple trace theory, we argue that memory retrieval is driven by internal and/or external factors which recreate these frequency-specific oscillatory patterns which occur during episodic encoding. These ideas are synthesized into a novel model of episodic memory (the spectro-contextual encoding and retrieval theory, or “SCERT”) that provides several testable predictions for future research.