ULTRASTRUCTURE OF ELECTRICALLY INDUCED OSTEOGENESIS IN THE RABBIT MEDULLARY CANAL
ULTRASTRUCTURE OF ELECTRICALLY INDUCED OSTEOGENESIS IN THE RABBIT MEDULLARY CANAL
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DOI：
10.1002/jor.1100040104
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发表时间：
1986-01-01
影响因子：
2.8
通讯作者：
HUNT, RM
中科院分区：
文献类型：
--
作者：
BRIGHTON, CT;HUNT, RM
将与插入非活性阴极的创伤相关的成年雄性新西兰白色兔的髓管中的超微结构变化与与从传递20 μ A恒定直流电的活性阴极电诱导骨生成相关的超微结构变化进行比较。在附近的一个非活性和一个活性阴极，髓管细胞内容物被取代的多态性细胞，后来成骨细胞新骨形成。多形细胞总是出现在毛细血管或其他血管的附近。随着时间的推移，在髓管周围的非活性阴极的新骨形成消失，而周围的活性阴极的新形成的数量逐渐增加。当髓管中围绕非活性阴极的新骨形成消失时，它被多形细胞网络所取代。当直流电施加到这样的非活性电极上时，多形细胞再次迅速被骨取代。多形细胞与成骨细胞的密切联系表明，前者可能是后者的前体细胞。
The ultrastructural changes in the medullary canal of the adult male New Zealand white rabbit associated with the trauma of the insertion of an inactive cathode were compared to that associated with electrically induced osteogenesis from an active cathode delivering 20 .mu.A constant direct current. In the vicinity of both an inactive and an active cathode, the medullary canal cellular content was replaced first by polymorphic cells and later by osteoblastic new bone formation. The polymorphic cells always appeared in the immediate vicinity of a capillary or other blood vessel. With time, the new bone formation in the medullary canal surrounding the inactive cathode disappeared, while new formation surrounding the active cathode progressively increased in amount. When the new bone formation in the medullary canal surrounding an inactive cathode disappeared, it was replaced by a network of polymorphic cells. When direct current was then applied to such an inactive electrode, the polymorphic cells were again rapidly replaced by bone. The close association of polymorphic cells with osteoblasts suggests that the former may be a precursor cell of the latter.