Morphometric analysis of cervical vertebrae in relation to mandibular growth
Morphometric analysis of cervical vertebrae in relation to mandibular growth
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DOI：
10.1016/j.ajodo.2015.06.028
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发表时间：
2016-01-01
影响因子：
3
通讯作者：
Farella, Mauro
中科院分区：
文献类型：
--
作者：
Gray, Sophie;Bennani, Hamza;Farella, Mauro
颈椎成熟（CVM）方法因其主观性而受到批评。本研究的目的是(1)分析第二至第四颈椎轮廓随生长的形态学变化，(2)检验CVM法测定下颌生长峰值的有效性。方法：从伯灵顿生长研究中获得25名年龄在10至16岁的参与者的侧位脑电图，并定性地确定CVM分期。然后对下颌和颈椎的半标志进行数字化，并使用点分布模型来描述与年龄和下颌生长高峰时间相关的椎体形态计量模板。混合模型分析用于确定下颌长度、性别、CVM分期和年龄之间的关系。结果：第二至第四颈椎在生长过程中的形态变化与CVM描述一致。然而，调整年龄后，下颌长度变化与CVM分期无显著相关性。下颌骨生长高峰前后椎体形状的形态测量模板相似，只有在生长高峰过去后才能检测到变化。形态测量椎体形状的变化在两性之间有所不同。结论：颈椎形态变化和CVM法不能准确识别下颌骨生长高峰。
Introduction: Cervical vertebral maturation (CVM) methods have been criticized because of their subjective nature. The aims of this study were (1) to analyze the morphometric changes in the outline of the second to fourth cervical vertebrae with growth and (2) to test the validity of the CVM method for determining the mandibular growth peak. Methods: Lateral cephalograms of 25 participants from ages 10 to 16 years were acquired from the Burlington Growth Study, and the CVM stage was qualitatively determined. Mandibular and cervical vertebral semilandmarks were then digitized, and point distribution models were used to describe the morphometric templates of the vertebrae in relation to chronologic age and the timing of peak mandibular growth. Mixed model analysis was used to determine the relationship between mandibular length, sex, CVM stage, and chronologic age. Results: Morphometric changes of the second to fourth cervical vertebrae during growth were consistent with the CVM descriptions. However, mandibular length changes were not significantly associated with CVM stages after adjusting for chronologic age. Morphometric templates of vertebral shapes before and during the mandibular growth peak were similar, with changes detectable only after the growth peak had passed. Morphometric vertebral shape changes varied between the sexes. Conclusions: Morphometric changes of the cervical vertebrae and the CVM method could not accurately identify the mandibular growth peak.