Tomato juice consumption improves blood antioxidative biomarkers in overweight and obese females
Tomato juice consumption improves blood antioxidative biomarkers in overweight and obese females
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DOI：
10.1016/j.clnu.2014.10.012
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发表时间：
2015-10-01
影响因子：
6.3
通讯作者：
Ghorbani, Mohammad
中科院分区：
文献类型：
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作者：
Ghavipour, Mahsa;Sotoudeh, Gity;Ghorbani, Mohammad
背景与目的：一些研究报道了番茄汁对氧化应激状态的有益作用。然而，在肥胖受试者的支持数据是稀缺的。本研究旨在确定番茄汁消费对超重和肥胖女性红细胞抗氧化酶，即超氧化物歧化酶（SOD），谷胱甘肽过氧化物酶（GPx）和过氧化氢酶（CAT），血浆总抗氧化能力（TAC）和血清丙二醛（MDA）的影响。对设拉子医科大学64名超重或肥胖（BMI = 25 kg/m2或更高）的女学生进行了随机对照临床试验。受试者随机接受番茄汁（n = 32，330 ml/d）或水（n = 28）20天。结果：干预组血浆总抗氧化酶（TAC）、红细胞抗氧化酶（RBC）活性明显升高，血清丙二醛（MDA）含量明显降低，与干预前和对照组比较差异有显著性（P < 0.05）。在干预组，类似的结果被发现在超重，但不是在肥胖，subjects.Conclusion：我们的研究结果表明，番茄汁降低氧化应激超重（可能肥胖）的女性，因此，可以预防肥胖相关疾病，促进健康。(C)2014爱思唯尔有限公司和欧洲临床营养与代谢学会。All rights reserved.
Background & aims: A few studies reported the beneficial effects of tomato juice on oxidative stress status. However, supporting data in obese subjects is scarce. This study aimed to determine the effects of tomato juice consumption on erythrocyte antioxidant enzymes, namely, superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT), plasma total antioxidant capacity (TAC), and serum malondialdehyde (MDA) in overweight and obese females.Methods: A randomized controlled clinical trial was conducted on 64 overweight or obese (BMI = 25 kg/m(2) or higher) female students of Shiraz University of Medical Sciences. Subjects randomly received tomato juice (n = 32, 330 ml/d) or water (n = 28) for 20 days. Daily dietary intake, anthropometric measures and blood antioxidant parameters were determined at the beginning and after 20 days intervention period.Results: Plasma TAC and erythrocyte antioxidant enzymes increased and serum MDA decreased in the intervention group compared with baseline and with the control group (p < 0.05). In the intervention group, similar results were found in overweight, but not in obese, subjects.Conclusion: Our results suggest that tomato juice reduces oxidative stress in overweight (and possibly obese) females and, therefore, may prevent from obesity related diseases and promote health. (C) 2014 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.