A journey into a Mediterranean diet and type 2 diabetes: a systematic review with meta-analyses.
A journey into a Mediterranean diet and type 2 diabetes: a systematic review with meta-analyses.
复制标题
DOI：
10.1136/bmjopen-2015-008222
复制
发表时间：
2015-08-10
期刊：
影响因子：
2.9
通讯作者：
Giugliano D
中科院分区：
文献类型：
--
作者：
Esposito K;Maiorino MI;Bellastella G;Chiodini P;Panagiotakos D;Giugliano D
总结地中海饮食在管理2型糖尿病和糖尿病前期状态方面的有效性的证据。对地中海饮食和对照饮食在治疗2型糖尿病和糖尿病前期状态方面的所有荟萃分析和随机对照试验(RCT)进行了系统的综述。电子搜索一直进行到2015年1月。如果他们的对照组接受另一种饮食治疗，如果他们有足够的持续时间(至少6个 月)，如果他们每组至少有30名参与者，则纳入试验进行荟萃分析。随机效应模型被用来汇集数据。患有或有患2型糖尿病风险的成年人。他们的饮食模式描述为使用“地中海式”的饮食模式。结果是血糖控制、心血管危险因素和代谢综合征的缓解。在2824项研究中，8项Meta分析和5项随机对照试验合格。对地中海饮食和糖尿病血糖控制的3项长期随机对照试验(>；6 月)进行的“从头开始”荟萃分析显示，与低脂饮食相比，地中海饮食更适合地中海饮食。另一项对两项长期随机对照试验的“从头开始”荟萃分析显示，代谢综合征缓解的可能性增加了49%。5荟萃分析显示，与其他饮食相比，地中海饮食对体重、总胆固醇和高密度脂蛋白胆固醇的影响是有利的。2荟萃分析表明，对地中海饮食的坚持程度越高，未来患糖尿病的风险就会降低19-23%。地中海饮食与包括低脂肪饮食在内的对照饮食相比，血糖控制和心血管风险因素更好，这表明地中海饮食适合2型糖尿病的整体管理。
To summarise the evidence about the efficacy of a Mediterranean diet on the management of type 2 diabetes and prediabetic states. A systematic review of all meta-analyses and randomised controlled trials (RCTs) that compared the Mediterranean diet with a control diet on the treatment of type 2 diabetes and prediabetic states was conducted. Electronic searches were carried out up to January 2015. Trials were included for meta-analyses if they had a control group treated with another diet, if they were of sufficient duration (at least 6 months), and if they had at least 30 participants in each arm. A random-effect model was used to pool data. Adults with or at risk for type 2 diabetes. Dietary patterns that described themselves as using a ‘Mediterranean’ dietary pattern. The outcomes were glycaemic control, cardiovascular risk factors and remission from the metabolic syndrome. From 2824 studies, 8 meta-analyses and 5 RCTs were eligible. A ‘de novo’ meta-analysis of 3 long-term (>6 months) RCTs of the Mediterranean diet and glycaemic control of diabetes favoured the Mediterranean diet as compared with lower fat diets. Another ‘de novo’ meta-analysis of two long-term RCTs showed a 49% increased probability of remission from the metabolic syndrome. 5 meta-analyses showed a favourable effect of the Mediterranean diet, as compared with other diets, on body weight, total cholesterol and high-density lipoprotein cholesterol. 2 meta-analyses demonstrated that higher adherence to the Mediterranean diet reduced the risk of future diabetes by 19–23%. The Mediterranean diet was associated with better glycaemic control and cardiovascular risk factors than control diets, including a lower fat diet, suggesting that it is suitable for the overall management of type 2 diabetes.