Blood contact activation: pathophysiological effects and therapeutic approaches

Blood contact activation: pathophysiological effects and therapeutic approaches
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血液接触激活:病理生理效应和治疗方法

DOI:
--
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发表时间:
1996
期刊:
Perfusion
影响因子:
--
通讯作者:
A. George
A. George
中科院分区:
--
文献类型:
--
作者:
P. Hornick;A. George

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a nonphysiologic manner. Perfusion is conducted using heparinization, haemodilution, pulsatile or nonpulsatile flow, and some degree of hypothermia. Oxygenation is achieved using membrane or bubble oxygenators. Significant clinical morbidity is relatively unusual, although this owes more to the body’s ability to compensate for the damaging effects of CPB than to extracorporeal circulatory perfection. CPB poses significant pathophysiological effects, principally from four areas; haemodynamics and perfusion,4-16 gaseous exchange,17-21 hypothermia and acid-base regulation22-28 and, finally, blood contact activation. Contact activation is caused when the formed
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DOI: 10.1016/0003-4975(94)90995-4
发表时间: 1994
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影响因子: --
作者:
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DOI: 10.1056/nejm198102263040901
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DOI: --
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影响因子: --
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Musial,J;Niewiarowski,S;Hershock,D;Morinelli,TA;Colman,RW;EdmundsJr,LH
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DOI: --
发表时间: 1982
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影响因子: --
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白细胞消耗可改善体外循环后自由基介导的肺损伤。
DOI: --
发表时间: 1990
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影响因子: --
作者:
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