PACCHIONI,ANTONIO (1665-1726) - EARLY STUDIES OF THE DURA-MATER
PACCHIONI,ANTONIO (1665-1726) - EARLY STUDIES OF THE DURA-MATER
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DOI：
10.3171/jns.1993.78.3.0515
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发表时间：
1993-03-01
影响因子：
4.1
通讯作者：
GIUFFRE, R
中科院分区：
文献类型：
--
作者：
BRUNORI, A;VAGNOZZI, R;GIUFFRE, R
蛛网膜绒毛沿着矢状窦聚集形成所谓的“帕奇奥尼颗粒”。这些结构最早是在1705年由意大利科学家Antonio Pacchioni描述的。帕基奥尼1665年出生于意大利的雷焦艾米利亚，并在那里获得医学学位。后来，他搬到了罗马，在那里他建立了一个成功的职业生涯，致力于医疗实践，研究和教学。他成为朋友的一些领先的科学家，他的年龄：兰西西，马尔皮吉，和Morgagni，等等。他致力于阐明硬脑膜的结构和功能，在他的研究中经常使用在各种液体中浸渍解剖标本的新技术。在Pacchioni的书面作品中，《Dissertatio Epistolaris de Glandulis Conglobatis Durae Meningis Humanae》（1705年）最值得考虑，因为它首次描述了蛛网膜颗粒。他将硬脑膜比作心肌，并将其归因于其“腺体”（腺体）分泌淋巴液的能力，以润滑收缩期间脑膜和大脑之间的滑动运动。Pacchioni于1726年在罗马去世三个世纪后，蛛网膜绒毛的精细结构尚未完全阐明;此外，许多与脑脊液吸收机制相关的问题仍然没有答案。
The clustering of arachnoid villi along the sagittal sinus forms what is known as ''Pacchioni granulations.'' These structures were first described in 1705 by Antonio Pacchioni, an italian scientist. Pacchioni was born in Reggio Emilia, Italy, in 1665, and there he received his degree in medicine. Later he moved to Rome where he built a successful career dedicated to medical practice, research, and teaching. He became a friend of some of the leading scientists of his age: Lancisi, Malpighi, and Morgagni, among others. He devoted himself to elucidating the structure and function of dura mater, and in his studies often used the new technique of maceration of anatomical specimens in various fluids. Among Pacchioni's written works, the Dissertatio Epistolaris de Glandulis Conglobatis Durae Meningis Humanae (1705) deserves the greatest consideration as it contains the first description of arachnoid granulations. He compared dura to cardiac muscle and attributed to its ''glandulae'' (glands) the faculty of secreting lymph for lubrication of the sliding movements between meninges and brain during contractions. Three centuries after Pacchioni's death in Rome in 1726, the fine structure of arachnoid villi has not been fully elucidated; moreover, many questions related to mechanisms underlying cerebrospinal fluid absorption remain unanswered.