L'activation sanguine au cours de l'assistance circulatoire mécanique prolongée

L'activation sanguine au cours de l'assistance circulatoire mécanique prolongée
复制标题

延长机械循环援助课程的积极乐观

DOI:
10.1016/j.patbio.2004.04.014
复制
发表时间:
2005
影响因子:
--
通讯作者:
D. Loisance
D. Loisance
中科院分区:
医学3区
文献类型:
--
作者:
M. Kirsch;E. Vermes;B. Boval;L. Tual;A. Mekontso;L. Drouet;D. Loisance

文献摘要

参考文献

被引文献

相似文献

机械循环支持已成为心源性休克或终末期心力衰竭患者的获批治疗选择。然而,心脏辅助装置的接受者容易发生出血、血栓栓塞和感染并发症。这些并发症的发生受到凝血和纤维蛋白溶解、炎症和免疫反应的全身性改变的影响。几项研究评价了接受脉动装置长期循环支持的患者的这些病理生理学变化。然而,最近推出的旋转血泵的系统性后果在很大程度上仍然未知。本文综述了使用脉动和非脉动装置进行长期循环支持的全身性后果。
Mechanical circulatory support has become an approved treatment option for patients with cardiogenic shock or end-stage heart failure. However, recipients of heart assist devices are prone to high incidences of bleeding, thrombo-embolic and infectious complications. The occurrence of these complications is favoured by systemic alterations of coagulation and fibrinolysis, inflammation and immune responses. Several studies have evaluated these pathophysiological changes in patients undergoing long term circulatory support with pulsatile devices. However, the systemic consequences of the more recently introduced rotary blood pumps remain largely unknown. The present review focuses on the systemic consequences of long term circulatory support with pulsatile and non-pulsatile devices.
DOI: 10.1056/nejmoa012175
发表时间: 2001-11-15
影响因子: 158.5
作者:
Rose, EA;Gelijns, AC;Meier, P
通讯作者: Meier, P
为什么体外循环会使患者生病:控制血液合成表面界面的策略。
DOI: --
发表时间: 1995
期刊: Advances in cardiac surgery.
影响因子: --
作者:
EdmundsJr,LH
通讯作者: EdmundsJr,LH