Therapy: Immunotherapy for T1DM--targeting innate immunity.

Therapy: Immunotherapy for T1DM--targeting innate immunity.
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治疗:T1DM 免疫疗法——针对先天免疫。

DOI:
10.1038/nrendo.2013.103
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发表时间:
2013
期刊:
Nature reviews. Endocrinology
影响因子:
--
通讯作者:
Wen,Li
Wen,Li
中科院分区:
--
文献类型:
--
作者:
Wong,FSusan;Wen,Li

文献摘要

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Two trials have assessed the use of canakinumab and anakinra in patients with new-onset type 1 diabetes mellitus (T1DM). Although fairly safe, the drugs were not efficacious in terms of halting the decline in β-cell function. Is this the end of the line for targeting IL-1 in T1DM?