A comparative study of rectal dose histograms in prostate brachytherapy: some analytic and numerical results.
A comparative study of rectal dose histograms in prostate brachytherapy: some analytic and numerical results.
复制标题
前列腺近距离放射治疗中直肠剂量直方图的比较研究：一些分析和数值结果。
DOI：
10.1118/1.1852811
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发表时间：
2005
期刊：
影响因子：
3.8
通讯作者：
Cormack,RobertA
中科院分区：
文献类型：
--
作者：
Song,JunS;Albert,Michele;D'Amico,AnthonyV;Cormack,RobertA
累积剂量直方图是在一个域上积分的积分函数的图形，根据区域的尺寸和结构，被称为剂量体积直方图（DVH），剂量表面直方图（DSH）或剂量壁直方图（DWH）。本文提出了一种比较研究的三个直肠剂量直方图为60例，以及一个圆柱形模型的直肠，特别是，DSH和DVH的圆柱形模型与一个点源的椭圆积分解析计算。60名患者的平均三个相对剂量直方图之间的差异小于5%，而不同壁厚的DVH和DWH之间的差异可能在范围内。本文还包含一个误差分析，使用两个简单的模型的直肠，真正的DSH和DWH可以通过数值积分计算，以评估数字化的效果。由于前列腺近距离放射治疗中直肠附近的低剂量梯度效应，数字化计算与数字化前的数值积分非常一致，在1%以内。
A cumulative dose histogram is the graph of an integral function integrated over a domain and is dubbed the dose‐volume histogram (DVH), the dose‐surface histogram (DSH) or the dose‐wall histogram (DWH), depending on the dimension and structure of the region . This paper presents a comparative study of the three rectal dose histograms for sixty patients as well as for a cylindrical model of the rectum; in particular, the DSH and DVH for the cylindrical model with one point source are computed analytically in terms of elliptic integrals. The difference among the three relative dose histograms, averaged over the sixty patients, is less than 5%, whereas that between DVH and DWH for various wall‐thickness can be as large as in the range . The paper also contains an error analysis using two simple models of the rectum, for which the true DSH and DWH can be computed via numerical integration, to evaluate the effect of digitization. The digitized computation agrees quite well with the pre‐digitization numerical integration, within 1% or , because of the low dose‐gradient effect near the rectum in prostate brachytherapy.