A new glucopyranoside from the leaves of Microsoriumfortunei

A new glucopyranoside from the leaves of Microsoriumfortunei
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一种来自 Microsoriumfortunei 叶的新吡喃葡萄糖苷

DOI:
10.1080/14786419.2020.1731745
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发表时间:
2020
影响因子:
2.2
通讯作者:
Chengqin Liang
Chengqin Liang
中科院分区:
化学3区
文献类型:
--
作者:
Mengqi Yan;Qin Luo;Xianli Zhou;Qinghu Mo;Caifeng Peng;Xiaoya Xian;Xiao Huang;Xinping Yang;Xu Chen;Chengqin Liang

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从云杉叶中分离得到一个新化合物2-hydroxy-4-[3’,5’-dihydroxyhexyl]phenyl-β-D-glucopyranoside(1)和5个已知化合物(2-6)。通过波谱技术,特别是二维核磁共振和MS数据分析,确定了它们的结构。这些化合物均为酚苷类化合物,均为首次从该植物中分离得到。化合物1对α-葡萄糖苷酶有中等抑制作用,IC50值为0.111 ± 0.061 mg/mL。
A new compound, 2-hydroxy-4-[3’,5’-dihydroxyhexyl]phenyl-β-D-glucopyranoside (1), together with five known compounds (2–6), were isolated from the leaves ofMicrosorium fortunei. Their structures were determined by spectroscopic techniques, especially 2D NMR and MS data analyses. All of these compounds are phenolic glycosides and were isolated from this plant for the first time. In addition, compound1showed moderate inhibitory activity against α-glucosidase with IC50value at 0.111 ± 0.061 mg/mL.