Using the KEGG database resource.
Using the KEGG database resource.
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DOI：
10.1002/0471250953.bi0112s11
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发表时间：
2012-06-01
影响因子：
--
通讯作者：
Kanehisa, Minoru
中科院分区：
文献类型：
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作者：
Tanabe, Mao;Kanehisa, Minoru
KEGG（京都基因和基因组百科全书）是一个生物信息学资源，用于从高层次和基因组的角度理解细胞和生物体的功能和效用。它是一个自给自足的、集成的资源，包括基因组、化学和网络信息，与许多外部数据库交叉引用，包含一套完整的构建模块（基因和分子）和接线图（相互作用网络），以表示细胞功能。本单元描述了使用KEGG、KEGG PATHWAY、KEGG基因、KEGG SSDB、KEGG表达和KEGG配体的协议。协议也描述了如何彩色地图，比较化合物和聚糖链，分析同源簇，可视化和分析微阵列数据，以及其他程序。所有这些协议都使用户能够充分利用KEGG提供的所有功能。KEGG（京都基因和基因组百科全书）是一个生物信息学资源，用于从高层次和基因组的角度理解细胞和生物体的功能和效用。它是一个自给自足的、集成的资源，包括基因组、化学和网络信息，并与许多外部数据库交叉引用。基因组和化学信息是一套完整的构建模块（基因和分子），网络信息包括分子接线图（相互作用/反应网络）和层次分类（关系网络），以表示高级功能。本单元描述了使用KEGG的协议，重点是KEGG PATHWAY、KEGG BRITE和KEGG MODULE中的分子网络信息，KEGG DISEASE和KEGG DRUG中的扰动分子网络，KEGG GENES和KEGG LIGAND中的分子构建块信息，以及KEGG ORTHOLOGY （KO）中基因组与分子网络连接的机制。所有这些协议都使用户能够充分利用KEGG提供的所有功能。
KEGG (Kyoto Encyclopedia of Genes and Genomes) is a bioinformatics resource for understanding the functions and utilities of cells and organisms from both high-level and genomic perspectives. It is a self-sufficient, integrated resource consisting of genomic, chemical, and network information, with cross-references to numerous outside databases, containing a complete set of building blocks (genes and molecules) and wiring diagrams (interaction networks) to represent cellular functions. This unit describes protocols for using KEGG, KEGG PATHWAY, KEGG GENES, KEGG SSDB, KEGG EXPRESSION, and KEGG LIGAND. Protocols are also described for how to color maps, compare chemical compounds and glycan chains, analyze Ortholog Clusters, and visualize and analyze microarray data, among other procedures. All of these many protocols enable the user to take advantage of the full breadth of the functionality provided by KEGG.KEGG (Kyoto Encyclopedia of Genes and Genomes) is a bioinformatics resource for understanding the functions and utilities of cells and organisms from both high-level and genomic perspectives. It is a self-sufficient, integrated resource consisting of genomic, chemical, and network information, with cross-references to numerous outside databases. The genomic and chemical information is a complete set of building blocks (genes and molecules) and the network information includes molecular wiring diagrams (interaction/reaction networks) and hierarchical classifications (relation networks) to represent high-level functions. This unit describes protocols for using KEGG, focusing on molecular network information in KEGG PATHWAY, KEGG BRITE, and KEGG MODULE, perturbed molecular networks in KEGG DISEASE and KEGG DRUG, molecular building block information in KEGG GENES and KEGG LIGAND, and a mechanism for linking genomes to molecular networks in KEGG ORTHOLOGY (KO). All of these many protocols enable the user to take advantage of the full breadth of the functionality provided by KEGG.