Monitoring cardiac output and left atrial pressure by analysis of the right ventricular pressure waveform based on missing output identification.
Monitoring cardiac output and left atrial pressure by analysis of the right ventricular pressure waveform based on missing output identification.
复制标题
通过基于缺失输出识别分析右心室压力波形来监测心输出量和左心房压力。
DOI：
10.1109/iembs.2009.5332740
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Mukkamala,Ramakrishna
中科院分区：
文献类型：
--
作者：
Xu,Da;Olivier,N;Mukkamala,Ramakrishna
一种经过验证的植入式设备现在可用于充血性心力衰竭患者右心室压力（RVP）波形的长期动态监测。然而，心输出量（CO）和左心房压力（LVEF）对于评估心脏功能和管理容量状态更有用。我们开发了一种新的技术来监测CO和CO2的RVP波形的基础上丢失的输出识别的分析。我们最初评估了该技术对金标准参考CO和CO2测量从两只狗在常见的血流动力学干预。我们报告的总体CO和CO2误差分别为13.3%和1.9 mmHg。随着进一步的成功测试，该技术可能与已建立的植入式设备一起使用，用于长期监测重要的血液动力学变量。
A proven implantable device is now available for long-term ambulatory monitoring of the right ventricular pressure (RVP) waveform of congestive heart failure patients. However, cardiac output (CO) and left atrial pressure (LAP) are far more useful for assessing cardiac function and managing volume status. We developed a new technique to monitor both CO and LAP by analysis of the RVP waveform based on missing output identification. We initially evaluated the technique against gold standard reference CO and LAP measurements from two dogs during common hemodynamic interventions. We report overall CO and LAP errors of 13.3% and 1.9 mmHg, respectively. With further successful testing, the technique may potentially be employed with an established implantable device for chronic monitoring of vital hemodynamic variables.