Multidomain Frailty in Heart Failure: Current Status and Future Perspectives
Multidomain Frailty in Heart Failure: Current Status and Future Perspectives
复制标题
心力衰竭的多域衰弱：现状和未来展望
DOI：
10.1007/s11897-021-00513-2
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发表时间：
2021
影响因子：
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通讯作者：
Matsue Yuya
中科院分区：
文献类型：
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作者：
Tanaka Shinya;Yamashita Masashi;Saito Hiroshi;Kamiya Kentaro;Maeda Daichi;Konishi Masaaki;Matsue Yuya
随着全球人口老龄化，虚弱和心力衰竭（HF）已成为心血管临床实践中迫切需要解决的问题。在这篇综述中，我们概述了心力衰竭患者虚弱的临床意义以及改善心力衰竭患者临床结果的潜在治疗策略。虚弱包括身体、心理和社会三个方面，每一个方面都是心衰患者预后的决定因素，尽管没有诊断虚弱的标准化标准，但每个方面都有重叠。虚弱可以通过各种干预措施进行靶向治疗，最近的研究表明，多学科干预可能是心力衰竭虚弱患者的一个有希望的选择。但目前数据有限，在临床应用前还需进一步研究。虚弱和HF有着共同的背景，彼此之间有着很强的相关性。需要制定更全面的虚弱评估和治疗干预措施，以进一步改善心衰虚弱患者的预后和生活质量。
Purpose of ReviewWith a worldwide aging population, frailty and heart failure (HF) have become issues that need to be addressed urgently in cardiovascular clinical practice. In this review, we outline the clinical implications of frailty in HF patients and the potential therapeutic strategies to improve the clinical outcomes of frail patients with HF.Recent FindingsFrailty has physical, psychological, and social domains, each of which is a prognostic determinant for patients with HF, and each domain overlaps with the other, although there are no standardized criteria for diagnosing frailty. Frailty can be targeted for treatment with various interventions, and recent studies have suggested that multidisciplinary intervention could be a promising option for frail patients with HF. However, currently, there is limited data, and further research is needed before its clinical implementation.SummaryFrailty and HF share a common background and are strongly associated with each other. More comprehensive assessment and therapeutic interventions for frailty need to be developed to further improve the prognosis and quality of life of frail patients with HF.