A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines.
A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines.
复制标题
DOI:
10.1021/ol200288w
复制
发表时间:
2011-04-01
期刊:
影响因子:
5.2
通讯作者:
Tang, Yi
中科院分区:
文献类型:
--
作者:
Qiao, Kangjian;Zhou, Hui;Xu, Wei;Zhang, Wenjun;Garg, Neil;Tang, Yi
A nonribosomal peptide synthetase-like enzyme (NRPS325) from Aspergillus terreus was reconstituted in vitro and was shown to synthesize thiopyrazines using an unprecedented mechanism. Substrate promiscuity of NRPS325 towards different amino acids and free thiols was explored to produce > 60 different thiopyrazine compounds.
登录
查看更多内容
影响因子:
15
作者:
Sims, James W.;Schmidt, Eric W.
通讯作者:
Schmidt, Eric W.
影响因子:
5.7
作者:
Samel, Stefan A.;Schoenafinger, Georg;Essen, Lars-Oliver
通讯作者:
Essen, Lars-Oliver
影响因子:
14.8
作者:
Bergmann, Sebastian;Schuemann, Julia;Hertweck, Christian
通讯作者:
Hertweck, Christian
DOI:
10.1038/nsb810
发表时间:
2002-07-01
期刊:
NATURE STRUCTURAL BIOLOGY
影响因子:
--
作者:
Keating, TA;Marshall, CG;Keating, AE
通讯作者:
Keating, AE
影响因子:
2.8
作者:
Dickschat, JS;Reichenbach, H;Schulz, S
通讯作者:
Schulz, S