Membrane phospholipid synthesis and endoplasmic reticulum function
Membrane phospholipid synthesis and endoplasmic reticulum function
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DOI：
10.1194/jlr.r800049-jlr200
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发表时间：
2009-04-01
影响因子：
6.5
通讯作者：
Jackowski, Suzanne
中科院分区：
文献类型：
--
作者：
Fagone, Paolo;Jackowski, Suzanne
本文综述了哺乳动物的磷脂合成和细胞的生化活动，产生膜脂质分子种类的位置。广义内质网室是膜脂质生物合成的中心站点，并讨论了脂质组成的改变，膜脂质生物合成的调节和细胞分泌功能之间的新兴关系的例子。Fagone，P.，和S.杰科斯基。膜磷脂合成与内质网功能。J. Lipid Res. 2009. S311-S316。
This review presents an overview of mammalian phospholipid synthesis and the cellular locations of the biochemical activities that produce membrane lipid molecular species. The generalized endoplasmic reticulum compartment is a central site for membrane lipid biogenesis, and examples of the emerging relationships between alterations in lipid composition, regulation of membrane lipid biogenesis, and cellular secretory function are discussed.-Fagone, P., and S. Jackowski. Membrane phospholipid synthesis and endoplasmic reticulum function. J. Lipid Res. 2009. S311-S316.