Preparation and biomedical applications of core-shell silica/magnetic nanoparticle composites.
Preparation and biomedical applications of core-shell silica/magnetic nanoparticle composites.
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DOI：
10.1166/jnn.2012.6428
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发表时间：
2012-04
影响因子：
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通讯作者：
Chuanyan Li;Chao Ma;F. Wang;Zhijiang Xil;Zhifei Wang;Yan Deng;Nongyue Hel
中科院分区：
文献类型：
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作者：
Chuanyan Li;Chao Ma;F. Wang;Zhijiang Xil;Zhifei Wang;Yan Deng;Nongyue Hel
核壳结构二氧化硅/磁性纳米颗粒复合材料因其具有保护核芯和赋予杂化结构新的性能而受到广泛的研究，使其在各个领域具有巨大的应用潜力。人们已经研究了几种制备磁性纳米颗粒包覆的二氧化硅的方法。这些方法包括STöber法、微乳化法、硅酸钠和正硅酸乙酯水解法、气溶胶热解法、逐层法、聚合物模板法和声化学沉积法。综述了制备二氧化硅/磁性纳米颗粒复合材料的最新合成路线和方法。此外，我们还介绍了这些纳米颗粒复合材料在生物医学领域的主要应用，并解决了高质量磁性纳米颗粒合成中的一些挑战。
Core-shell structured silica/magnetic nanoparticle composites have recently been subjected to extensive research since the shells could offer protection to the cores and introduce new properties to the hybrid structures, which endue them with great application potentials in various fields. Several approaches have been studied for the synthesis of SiO2 coated on magnetic nanoparticles. These approaches include Stöber process, microemulsion, sodium silicate and tetraethoxysilane hydrolysis, aerosol pyrolysis, layer-by-layer strategy, polymer-templating and sonochemical deposition. This review is focused on describing state-of-the-art synthetic routes and methods for the preparation of silica/magnetic nanoparticle composites. Furthermore, we also introduce main applications of these nanoparticle composites in biomedical scopes and address some challenges in the synthesis of high-quality magnetic nanoparticles.