CD4/CD8 ratio normalisation and non-AIDS-related events in individuals with HIV who achieve viral load suppression with antiretroviral therapy: an observational cohort study
CD4/CD8 ratio normalisation and non-AIDS-related events in individuals with HIV who achieve viral load suppression with antiretroviral therapy: an observational cohort study
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DOI：
10.1016/s2352-3018(15)00006-5
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发表时间：
2015-03-01
期刊：
影响因子：
16.1
通讯作者：
Monforte, Antonella d'Arminio
中科院分区：
文献类型：
--
作者：
Mussini, Cristina;Lorenzini, Patrizia;Monforte, Antonella d'Arminio
背景在HIV患者中，抗逆转录病毒治疗（ART）后的免疫重建通常不完全。我们评估的概率达到1或以上的患者开始ART后，其与非艾滋病定义的事件和death.Methods的发病，我们做了分析的ICONA队列，招募初治的HIV患者在意大利的CD 4/CD 8比。我们纳入了队列中开始ART的参与者，达到了无法检测的病毒载量（
Background In patients with HIV, immune reconstitution after antiretroviral therapy (ART) is often incomplete. We assessed the probability of patients reaching a CD4/CD8 ratio of 1 or more after the start of ART and its association with the onset of non-AIDS-defi ning events and death.Methods We did an analysis of the ICONA cohort, which recruited treatment-naive patients with HIV in Italy. We included participants in the cohort who started ART, reached an undetectable viral load (