Cardiac MR: Imaging of the Foetal Heart Dynamics using Doppler Ultrasound Triggering
Cardiac MR: Imaging of the Foetal Heart Dynamics using Doppler Ultrasound Triggering
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DOI：
10.1515/bmt-2012-4443
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发表时间：
2012-09-01
影响因子：
1.7
通讯作者：
Wedegaertner, Ulrike
中科院分区：
文献类型：
--
作者：
Ueberle, Friedrich;Dettmann, Eike;Wedegaertner, Ulrike
磁共振成像 (MRI) 对于胎儿心脏成像非常重要，尤其是诊断心脏和大血管的异常。虽然在成人心脏成像中，MR 触发可以通过心电图 (ECG) 或手指脉搏血氧饱和度 (POX) 来完成，但这些方法无法应用，因为胎儿位于子宫内。该项目的目的是证明使用多普勒超声通过胎儿心跳非侵入性触发 MR 的可行性。使用无伪影多普勒传感器来拾取心脏运动信号。开发了一种允许触发 MR 系统的算法。在一项动物研究中，使用 1.5T 扫描仪对 9 只怀孕母羊成功进行了胎羊心脏成像。使用专用软件，可以以良好的分辨率记录胎儿心跳的 MR 电影序列以及 124 天胎儿心脏结构的标准两腔和四腔图像。
Magnetic Resonance Imaging (MRI) could be of high importance for imaging the foetal heart, especially to diagnose anomalies of the heart and the great vessels. While in the imaging of adult hearts MR triggering can be done through Electro-Cardiogram (ECG) or finger pulse oximetry (POX), these methods cannot apply because the foetus lies within the uterus. The aim of this project was to demonstrate the feasibility of non-invasive triggering of the MR by the foetal heart beat using Doppler Ultrasound. An artefact-free Doppler transducer was used to pick up the heart motion signals. An algorithm was developed which allowed triggering of the MR system. In an animal study, successful imaging of the foetal sheep heart was performed on 9 pregnant ewes at a 1.5T scanner. With dedicated software, MR cine sequences of the foetal heart beat and standard two- and four chamber images of the structures of the hearts of 124 days old foetuses could be recorded with a good resolution.