STEROID RESPONSIVE NEPHROTIC SYNDROME IS MORE COMMON IN ASIANS

STEROID RESPONSIVE NEPHROTIC SYNDROME IS MORE COMMON IN ASIANS
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DOI:
10.1136/adc.60.11.1014
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发表时间:
1985-01-01
影响因子:
5.2
通讯作者:
WHITE, RHR
WHITE, RHR
中科院分区:
医学2区
文献类型:
--
作者:
SHARPLES, PM;POULTON, J;WHITE, RHR

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进行了一项回顾性研究,以确定在英国出生并居住在伯明翰的亚洲、欧洲和非洲裔加勒比儿童的类固醇反应性肾病综合征的发病率并比较其自然史。患者的身份是根据 1979 年至 1983 年期间的入院记录确定的。基线人口数据是使用城市出生统计数据从同一地区获得的。其中有 27 名亚洲患者、13 名欧洲患者和 2 名加勒比非洲裔患者,年发病率分别为每 100,000 名儿童 16 例、2.6 例和 3.1 例。亚洲儿童的发病率高出六倍仍然无法解释;进一步的流行病学研究可能会为病因学提供新的线索。
A retrospective study was undertaken to determine the incidence and compare the natural history of steroid responsive nephrotic syndrome in Asian, European, and Afro-Caribbean children born in the United Kingdom and living in Birmingham. Patients were identified from hospital admission records during the years 1979-1983. Baseline population data were obtained from the same area using city birth statistics. There were 27 Asian, 13 European, and 2 Afro-Caribbean patients, giving annual incidences of 16, 2.6, and 3.1 per 100,000 children. The sixfold higher incidence in Asian children remains unexplained; further epidemiological studies may throw new light on the aetiology.