Representativeness of Participants in the Cancer Care Outcomes Research and Surveillance Consortium Relative to the Surveillance, Epidemiology, and End Results Program
Representativeness of Participants in the Cancer Care Outcomes Research and Surveillance Consortium Relative to the Surveillance, Epidemiology, and End Results Program
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DOI：
10.1097/mlr.0b013e318222a711
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发表时间：
2013-02-01
期刊：
影响因子：
3
通讯作者：
Harrington, David P.
中科院分区：
文献类型：
--
作者：
Catalano, Paul J.;Ayanian, John Z.;Harrington, David P.
背景：癌症治疗结果研究和监测（CanCORS）联盟的研究目标是确定患者、提供者和卫生保健组织的特征和信念如何影响新诊断的肺癌和结直肠癌患者的治疗和结果。由于CanCORS的结果将为国家政策提供信息，因此了解它们如何推广到患有这些癌症的美国人口是很重要的。研究设计：本研究评估了2003年至2005年间入选的10,547例肺癌（LC）或结直肠癌（CRC）的CanCORS队列的代表性。我们将特征（性别、种族、年龄和疾病分期）与监测、流行病学和最终结果（SEER）人群（234,464例在CanCORS招募期间新发这些癌症的患者）进行了比较。结果：canors样本与两种癌症的SEER方案匹配良好。在CanCORS中，41% LC/47% CRC为女性，而在SEER中，47% LC/49% CRC为女性。非裔美国人、西班牙裔和亚洲病例在CanCORS和SEER之间的差异不超过5个百分点。SEER人群年龄稍大，年龄在75岁以上的患者比例在SEER中为33.1% LC/37.3% CRC，而在CanCORS中为26.9% LC/29.4%，并且早期患者的比例也略高。我们还发现，CanCORS队列在特定的SEER区域具有代表性，这些区域与CanCORS位点密切相关。结论：本研究表明，canors联盟成功地在canors区域内招募了具有人口统计学代表性的样本。
Background: The research goals of the Cancer Care Outcomes Research and Surveillance (CanCORS) Consortium are to determine how characteristics and beliefs of patients, providers, and health care organizations influence the treatments and outcomes of individuals with newly diagnosed lung and colorectal cancers. As CanCORS results will inform national policy, it is important to know how they generalize to the United States population with these cancers.Research Design: This study assessed the representativeness of the CanCORS cohort of 10,547 patients with lung cancer (LC) or colorectal cancer (CRC) enrolled between 2003 and 2005. We compared characteristics (sex, race, age, and disease stage) with the Surveillance, Epidemiology, and End Results (SEER) population of 234,464 patients with new onset of these cancers during the CanCORS recruitment period.Results: The CanCORS sample is well matched to the SEER Program for both cancers. In CanCORS, 41% LC/47% CRC were female versus 47% LC/49% CRC in SEER. African American, Hispanic, and Asian cases differed by no more than 5 percentage points between CanCORS and SEER. The SEER population is slightly older, with the percentage of patients older than 75 years 33.1% LC/37.3% CRC in SEER versus 26.9% LC/29.4% in CanCORS, and also has a slightly higher proportion of early stage patients. We also found that the CanCORS cohort was representative within specific SEER regions that map closely to CanCORS sites.Conclusions: This study demonstrates that the CanCORS Consortium was successful in enrolling a demographically representative sample within the CanCORS regions.