The incidence of primary angle-closure glaucoma in Olmsted County, Minnesota

The incidence of primary angle-closure glaucoma in Olmsted County, Minnesota
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DOI:
10.1001/archopht.1997.01100150179005
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发表时间:
1997-02-01
影响因子:
--
通讯作者:
Gray, DT
Gray, DT
中科院分区:
其他
文献类型:
--
作者:
Erie, JC;Hodge, DO;Gray, DT

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目的:确定原发性闭角型青光眼(PACG)的发病率并评估接受PACG治疗的患者的视力结果。设计:基于人群的回顾性发病率研究。设置和患者:明尼苏达州奥姆斯特德县的居民,年龄40岁及以上,在1980年1月1日至1992年12月31日的13年期间诊断为PACG。主要结果测量:通过明尼苏达州罗切斯特的马约诊所的医学诊断指数和罗切斯特流行病学项目确定PACG的事件病例。年龄和性别调整后的平均年发病率为每10万名40岁及以上人群8.3(95%置信区间,5.6-11.0)。诊断时与PACG相关的单眼失明概率为14%。在确诊时非单眼盲的患者中,PACG导致单眼盲的5年概率为4%。结论:原发性闭角型青光眼是一种少见的疾病。大多数被PACG致盲的患者在诊断时是盲的。
Objectives: To determine the incidence of primary angle-closure glaucoma (PACG) and to assess the visual outcomes of patients treated for PACG.Design: Population-based retrospective incidence study.Setting and Patients: Residents of Olmsted County, Minnesota, aged 40 years and older and diagnosed with PACG in the 13-year period between January 1, 1980, and December 31, 1992.Main Outcome Measure: Incident cases of PACG identified through the Medical Diagnostic Index of Mayo Clinic, Rochester, Minn, and the Rochester Epidemiology Project.Results: Thirty-six incident cases were identified. The mean annual age- and sex-adjusted incidence per 100 000 people aged 40 years and older was 8.3 (95% confidence interval, 5.6-11.0). The probability of monocular blindness associated with PACG at the time of diagnosis was 14%. Among patients not monocularly blind at diagnosis, the 5-year probability of developing monocular blindness associated with PACG was 4%.Conclusions: Primary angle-closure glaucoma is an uncommon disease in our community. Most of the patients blinded by PACG were blind at the time the condition was diagnosed.