Effects of Moderate Salt Restriction on Intralymphocytic Sodium and Pressor Response to Stress in Borderline Hypertension
Effects of Moderate Salt Restriction on Intralymphocytic Sodium and Pressor Response to Stress in Borderline Hypertension
复制标题
适度限盐对临界高血压患者淋巴细胞内钠和应激反应的影响
DOI：
10.1161/01.hyp.4.6.789
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发表时间：
1982
期刊：
影响因子：
8.3
通讯作者：
Bruno Magnani
中科院分区：
文献类型：
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作者：
Ettore Ambrosioni;F. Costa;Claudio Borghi;L. Montebugnoli;M. Giordani;Bruno Magnani
在 25 名患有边缘性高血压的年轻受试者中测试了适度饮食盐限制对淋巴细胞内钠含量和对压力（心算、握力和自行车运动）的升压反应的影响。该研究是通过随机、交叉、患者内实验设计进行的。饮食并不能显着降低静息时的血压，但可以显着降低压力和运动时的收缩压和舒张压。在低盐饮食之前和期间，刺激引起的舒张压变化与淋巴细胞内钠含量显着相关，而收缩压和心率变化则没有发现相关性。这些发现表明，在患有边缘性高血压的年轻受试者中，钠稳态和血压调节在某种程度上是相互关联的，并且适度的饮食盐限制会降低淋巴细胞内的钠含量和对肾上腺素能刺激的升压反应。这可能有助于预防持续性高血压的发展。 （高血压 4：789–794，1982）
The effects of a moderate dietary salt restriction on intralymphocytic sodium content and pressor response to stress (mental arithmetic, handgrip, and bicycle exercise) were tested in 25 young subjects with borderline hypertension. The study was performed by a randomized, cross-over, within-patient, experimental design. Diet did not significantly reduce blood pressure at rest but did so significantly in both systolic and diastolic blood pressure during stress and exercise. Variations in diastolic blood pressure induced by stimulation correlated significantly with intralymphocytic sodium content both before and during low-salt diet whereas no correlation was found in the case of systolic blood pressure and heart rate variations. These findings suggest that in young subjects with borderline hypertension, sodium homeostasis and blood pressure regulation are somehow interrelated, and that a moderate dietary salt restriction reduces both intralymphocytic sodium content and pressor response to adrenergic stimulation. This could be useful in preventing the development of sustained hypertension. (Hypertension 4: 789–794, 1982)
改变高血压动脉肌肉收缩的膜电位控制。
DOI：
--
发表时间：
1985
期刊：
Klinische Wochenschrift
影响因子：
--
作者：
Hermsmeyer,K
通讯作者：
Hermsmeyer,K