Nanocarrier-loaded block copolymer dual domain organogels
Nanocarrier-loaded block copolymer dual domain organogels
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DOI：
10.1016/j.polymer.2020.123246
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发表时间：
2021-01-15
期刊：
影响因子：
4.6
通讯作者：
Lee, Byeongdu
中科院分区：
文献类型：
--
作者：
Mineart, Kenneth P.;Walker, William W.;Lee, Byeongdu
负载的聚合物凝胶是控制释放领域中的普遍材料，并且最近已经配制成包括纳米载体域，例如胶束和囊泡。用于建立凝胶的固体状特性的一种机制是嵌段共聚物自组装，其可以产生跨越系统的物理交联网络。纳米载体和交联结构域的组合提供了具有丰富的纳米级相空间的凝胶，能够进行复杂的宏观性质调节。本手稿提供了纳米载体负载的嵌段共聚物有机凝胶的概述，其中纳米载体是由二辛基磺基琥珀酸钠（AOT）形成的反胶束，嵌段共聚物是苯乙烯阿坝三嵌段共聚物，并且凝胶溶剂是脂肪族矿物油。该介绍性概述开始于确定其中形成纳米载体负载的嵌段共聚物有机凝胶（2-49重量%三嵌段共聚物和8 × 10（-3）-1重量% AOT）的三元相空间中的包络。接下来，详细的纳米结构描述的凝胶在AOT和三嵌段共聚物的浓度变化。该手稿的结论与演示AOT反胶束释放和凝胶单轴拉伸响应的凝胶含有0-1重量%的AOT和5-40重量%的苯乙烯三嵌段共聚物。
Loaded polymer gels are prevalent materials in the controlled release community and, fairly recently, have been formulated to include nanocarrier domains such as micelles and vesicles. One mechanism used to establish the solid-like characteristic of gels is block copolymer self-assembly, which can result in a system-spanning, physically-crosslinked network. The combination of nanocarrier and crosslink domain presence offers gels with a rich nanoscale phase space capable of intricate macroscopic property tuning. The current manuscript provides an overview of nanocarrier-loaded block copolymer organogels wherein nanocarriers are reverse micelles formed by sodium dioctyl sulfosuccinate (AOT), the block copolymer is a styrenic ABA triblock copolymer, and the gel solvent is aliphatic mineral oil. This introductory overview starts by identifying the envelope in ternary phase space wherein nanocarrier-loaded block copolymer organogels form (2-49 wt% triblock copolymer and 8x10(-3)-1 wt% AOT). Next, a detailed nanostructural description of gels varying in AOT and triblock copolymer concentration is presented. The manuscript concludes with demonstration of AOT reverse micelle release and gel uniaxial tensile response for gels containing 0-1 wt% AOT and 5-40 wt% styrenic triblock copolymer.