Three-dimensional flow-independent peripheral angiography
Three-dimensional flow-independent peripheral angiography
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DOI：
10.1002/mrm.1910380302
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发表时间：
1997-09-01
影响因子：
3.3
通讯作者：
Nishimura, DG
中科院分区：
文献类型：
--
作者：
Brittain, JH;Olcott, EW;Nishimura, DG
一个磁化制备序列，T-2- prep - ir，利用T-1， T-2和化学位移差异来抑制相对于动脉血的背景组织，由此产生的血流无关的血管造影可以描绘任意方向和流速的血管，不需要外源性造影剂，肌肉是正常志愿者的主要背景信号来源。然而，在一些患者中，长t -2深静脉血和非血管液体（如水肿）也可作为背景信号。描述了三组成像参数，以满足患者特定的对比要求。一个快速的，基于螺旋的，三维读数用于生成下肢的高分辨率血管造影。与x线血管造影和二维飞行时间血管造影的比较表明，这种与血流无关的技术具有独特的能力，可以准确地描绘狭窄，并显示缓慢流动的平面血管。
A magnetization-prepared sequence, T-2-Prep-IR, exploits T-1, T-2, and chemical shift differences to suppress background tissues relative to arterial blood, The resulting flow-independent angiograms depict vessels with any orientation and flow velocity, No extrinsic contrast agent is required, Muscle is the dominant source of background signal in normal volunteers. However, long-T-2 deep venous blood and nonvascular fluids such as edema also contribute background signal in some patients. Three sets of imaging parameters are described to address patient-specific contrast requirements, A rapid, spiral-based, three-dimensional readout is utilized to generate high-resolution angiograms of the lower extremities. Comparisons with x-ray angiography and two-dimensional time-of-flight angiography indicate that this flow-independent technique has unique capabilities to accurately depict stenoses and to visualize slow flow and in-plane vessels.