Validity Properties of a Self-reported Modified Frailty Phenotype Among People With HIV in Clinical Care in the United States.
Validity Properties of a Self-reported Modified Frailty Phenotype Among People With HIV in Clinical Care in the United States.
复制标题
DOI：
10.1097/jnc.0000000000000389
复制
发表时间：
2023-03-01
影响因子：
2
通讯作者：
Delaney, Joseph A. C.
中科院分区：
文献类型：
--
作者：
Ruderman, Stephanie A.;Webel, Allison R.;Willig, Amanda L.;Drumright, Lydia N.;Fitzpatrick, Annette L.;Odden, Michelle C.;Cleveland, John D.;Burkholder, Greer;Davey, Christine H.;Fleming, Julia;Buford, Thomas W.;Jones, Raymond;Nance, Robin M.;Whitney, Bridget M.;Mixson, L. Sarah;Hahn, Andrew W.;Mayer, Kenneth H.;Greene, Meredith;Saag, Michael S.;Kamen, Charles;Pandya, Chintan;Lober, William B.;Kitahata, Mari M.;Crane, Paul K.;Crane, Heidi M.;Delaney, Joseph A. C.
Fried's frailty phenotype（FFP）是常见的。我们评估了一种自我报告的改良脆弱表型（Mod-FP），用于HIV感染者（PWH）。在522名从事两项纵向研究的PWH中，我们评估了四项Mod-FP与五项FFP的效度。我们通过受试者操作者特征曲线比较了表型，对虚弱进行分类的一致性，以及通过与经历过福尔斯的相关性比较了标准有效性。Mod-FP将8%的PWH分类为虚弱，而FFP将9%分类为虚弱。Mod-FP分类虚弱的受试者工作特征曲线下面积为0.93（95% CI = 0.91-0.96）。我们观察到，对虚弱状态进行分类的Kappa值范围为0.64（未加权）至0.75（加权）。两种定义都发现虚弱与跌倒的可能性更大有关; FFP估计的幅度略大（即，或）的关联比Mod-FP。Mod-FP在测量PWH中的脆弱性方面具有良好的性能，并且当观察评估的金标准（即，慢和慢是不可行的。
Modifications to Fried’s frailty phenotype (FFP) are common. We evaluated a self-reported modified frailty phenotype (Mod-FP) used among people with HIV (PWH). Among 522 PWH engaged in two longitudinal studies, we assessed validity of the four-item Mod-FP compared with the five-item FFP. We compared the phenotypes via receiver operator characteristic curves, agreement in classifying frailty, and criterion validity via association with having experienced falls. Mod-FP classified 8% of PWH as frail, whereas FFP classified 9%. The area under the receiver operator characteristic curve for Mod-FP classifying frailty was 0.93 (95% CI = 0.91–0.96). We observed kappa ranging from 0.64 (unweighted) to 0.75 (weighted) for categorizing frailty status. Both definitions found frailty associated with a greater odds of experiencing a fall; FFP estimated a slightly greater magnitude (i.e., OR) for the association than Mod-FP. The Mod-FP has good performance in measuring frailty among PWH and is reasonable to use when the gold standards of observed assessments (i.e., weakness and slowness) are not feasible.
DOI：
10.3904/kjim.2019.172
发表时间：
2021-03
期刊：
The Korean journal of internal medicine
影响因子：
--
作者：
Jung HW;Kim S;Won CW
通讯作者：
Won CW