Use of microsatellite markers and gene dosage to quantify gene copy numbers in Candida albicans
Use of microsatellite markers and gene dosage to quantify gene copy numbers in Candida albicans
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DOI：
10.1128/jcm.43.3.1387-1389.2005
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发表时间：
2005-03-01
影响因子：
9.4
通讯作者：
Bretagne, S
中科院分区：
文献类型：
--
作者：
Costa, JM;Eloy, O;Bretagne, S
利用微卫星标记分型，必须知道等位基因的数目，以计算二倍体白念珠菌中给定位点的等位基因频率。我们描述了一个基因剂量与双重实时PCR。这样的剂量在探索C.白色念珠菌
With microsatellite marker typing, the number of alleles must be known for calculation of allelic frequencies in the diploid Candida albicans for a given locus. We describe a gene dosage with a double real-time PCR. Such a dosage should also be useful in exploring the loss of heterozygosity in C. albicans.