Simple and Rapid High-Yield Synthesis and Size Sorting of Multibranched Hollow Gold Nanoparticles with Highly Tunable NIR Plasmon Resonances
Simple and Rapid High-Yield Synthesis and Size Sorting of Multibranched Hollow Gold Nanoparticles with Highly Tunable NIR Plasmon Resonances
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DOI：
10.1002/smll.201500095
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发表时间：
2015-09-16
期刊：
影响因子：
13.3
通讯作者：
Rodriguez-Fernandez, Jessica
中科院分区：
文献类型：
--
作者：
Blanch, Adam J.;Doeblinger, Markus;Rodriguez-Fernandez, Jessica
具有尖锐尖端的分支金纳米颗粒被认为是传感和场增强应用的优秀候选者。在这里，提出了一种快速，简单的合成策略，产生高度支化的金纳米粒子与中空的核心和约。100%的收率，通过一个简单的一锅无籽反应，在室温下，在Triton X-100的存在下。结果表明，通过调节反应物的浓度，可以得到尺寸、分支密度和分支长度可调的多分支空心金纳米粒子。对形成机制的深入了解指向一种聚合型的生长，首先是中空核心的形成，然后是分支。纳米颗粒的明显的近红外（NIR）等离子体激元带是由于中空性和分支的组合贡献，并且可以在宽范围（近似700-2000 nm）内调谐。它还表明，基于多分支的中空金纳米粒子的胶体分散体的高环境敏感性，可以进一步提高通过分离的纳米粒子到给定的大小和改进的单分散性的部分通过甘油密度梯度。获得具有可预测的尺寸（50-300 nm）和支化的高度单分散的多支化中空金纳米颗粒的可能性，以及因此定制的NIR等离子体特性，突出了它们在治疗诊断应用中的潜力。
Branched gold nanoparticles with sharp tips are considered excellent candidates for sensing and field enhancement applications. Here, a rapid and simple synthesis strategy is presented that generates highly branched gold nanoparticles with hollow cores and a ca.100% yield through a simple one-pot seedless reaction at room temperature in the presence of Triton X-100. It is shown that multibranched hollow gold nanoparticles of tunable dimensions, branch density and branch length can be obtained by adjusting the concentrations of the reactants. Insights into the formation mechanism point toward an aggregative type of growth involving hollow core formation first, and branching thereafter. The pronounced near-infrared (NIR) plasmon band of the nanoparticles is due to the combined contribution from hollowness and branching, and can be tuned over a wide range (approximate to 700-2000 nm). It is also demonstrated that the high environmental sensitivity of colloidal dispersions based on multibranched hollow gold nanoparticles can be boosted even further by separating the nanoparticles into fractions of given sizes and improved monodispersity by means of a glycerol density gradient. The possibility to obtain highly monodisperse multibranched hollow gold nanoparticles with predictable dimensions (50-300 nm) and branching and, therefore, tailored NIR plasmonic properties, highlights their potential for theranostic applications.