Improved Detection of Sentinel Lymph Nodes in SPECT/CT Images Acquired Using a Low- to Medium-Energy General-Purpose Collimator
Improved Detection of Sentinel Lymph Nodes in SPECT/CT Images Acquired Using a Low- to Medium-Energy General-Purpose Collimator
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DOI：
10.1097/rlu.0b013e31828da362
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发表时间：
2014-01-01
影响因子：
10.6
通讯作者：
Kinuya, Seigo
中科院分区：
文献类型：
--
作者：
Yoneyama, Hiroto;Tsushima, Hiroyuki;Kinuya, Seigo
目的：使用低能量高分辨率（LEHR）准直器进行淋巴管造影会导致注射部位出现星形伪影。本研究的目的是确认是否低到中等能量的通用（LMEGP）准直器的分辨率较低的补偿间隔渗透和减少星形artifaction.Methods的程度减少：共106例女性乳腺癌患者，活检诊断，参加了这项研究。肿瘤周围注射Tc-99 mPhytate（37 MBq，1 mCi），3 ~ 4 h后行平面及SPECT/CT显像。结果：LEHR和LEHR + LMEGP准直器的平面显像分别在96.2%（102/106）和99.1%（105/106）的患者中检出前哨淋巴结（SLN）。使用LEHR和LEHR + LMEGP准直器的平面和SPECT/CT成像相结合，SLN的阳性识别率分别为97.2%（103/106）和100%（106/106）。LMEGP准直器的使用改善了SLN的检测。
Purpose: The use of the low-energy high-resolution (LEHR) collimator for lymphoscintigraphy causes the appearance of star-shaped artifacts at injection sites. The aim of this study was to confirm whether the lower resolution of the low-to medium-energy general-purpose (LMEGP) collimator is compensated by decrease in the degree of septal penetration and the reduction in star-shaped artifacts.Methods: A total of 106 female patients with breast cancer, diagnosed by biopsy, were enrolled in this study. Tc-99m phytate (37 MBq, 1 mCi) was injected around the tumor, and planar and SPECT/CT images were obtained after 3 to 4 hours. When sentinel lymph nodes (SLNs) could not be identified from planar and SPECT/CT images by using the LEHR collimator, we repeated the study with the LMEGP collimator.Results: Planar imaging performed using the LEHR and LEHR + LMEGP collimators positively identified SLNs in 96.2% (102/106) and 99.1% (105/106) of the patients, respectively. Using combination of planar and SPECT/CT imaging with the LEHR and LEHR + LMEGP collimators, SLNs were positively identified in 97.2% (103/106) and 100% (106/106) of the patients, respectively.Conclusions: The LMEGP collimator provided better results than the LEHR collimator because of the lower degree of septal penetration. The use of the LMEGP collimator improved SLN detection.