Prevalence trends of selected major birth defects: A multi-state population-based retrospective study, United States, 1999 to 2007
Prevalence trends of selected major birth defects: A multi-state population-based retrospective study, United States, 1999 to 2007
复制标题
DOI：
10.1002/bdr2.1113
复制
发表时间：
2017-11-01
影响因子：
2.1
通讯作者：
Kirby, Russell S.
中科院分区：
文献类型：
--
作者：
St Louis, Amanda M.;Kim, Keewan;Kirby, Russell S.
背景：我们评估了选定的出生缺陷超过9年的时间，以评估患病率的趋势，选定的孕产妇和婴儿factors.Methods数据汇总从11个人口为基础的出生缺陷监测计划在美国1999年和2007年之间出生的儿童。计算了26种特定出生缺陷的总体患病率以及3年间隔患病率，并按母亲年龄、母亲种族/民族和婴儿性别分层。计算每种出生缺陷的平均年变化百分比（AAPC）。Poisson回归用于确定AAPC的变化，joinpoint回归用于确定每种缺陷患病率随时间推移的断点和斜率变化。结果在1999年至2001年以及2005年至2007年期间，四种出生缺陷增加了10%或更多：主动脉缩窄（17%）、腹裂（83%）、脐膨出（11%）和唐氏综合征（10%）。母亲中
Background We evaluated selected birth defects over a 9-year period to assess prevalence trends by selected maternal and infant factors.Methods Data were pooled from 11 population-based birth defects surveillance programs in the United States for children born between 1999 and 2007. Overall prevalence, as well as 3-year interval prevalence, was calculated for 26 specific birth defects, stratified by maternal age, maternal race/ethnicity, and infant sex. Average annual percent change (AAPC) was calculated for each birth defect. Poisson regression was used to determine change in AAPC, and joinpoint regression to identify breakpoints and changes in slope for prevalence of each defect over time.Results Between 1999 and 2001 and 2005 and 2007, four birth defects increased by 10% or more: coarctation of the aorta (17%), gastroschisis (83%), omphalocele (11%), and Down syndrome (10%). Among mothers