Early development of changes in cortical representation of C3 vibrissa following neonatal denervation of surrounding vibrissa receptors: A 2-deoxyglucose study in the rat
Early development of changes in cortical representation of C3 vibrissa following neonatal denervation of surrounding vibrissa receptors: A 2-deoxyglucose study in the rat
复制标题
新生儿周围触须受体去神经后 C3 触须皮质表征变化的早期发展：大鼠 2-脱氧葡萄糖研究
DOI：
10.1016/0304-3940(84)90190-3
复制
发表时间：
1984
影响因子：
2.5
通讯作者：
P. Hand
中科院分区：
文献类型：
--
作者：
M. Kossut;P. Hand
在新生儿单侧消融除 C3 须毛囊之外的所有毛囊后，用 [14C]2-脱氧葡萄糖 (2-DG) 放射自显影术研究了大鼠 C3 须毛的皮质表征变化的发展。通过抚摸幸存的 C3 触须产生的 2-DG 标记柱在出生后第 5 天扩大 (35%)，到出生后第 5 天扩大到 140%。如图12所示，与对侧半球的对照C3触须柱相比。在所有年龄段，受累侧 C3 桶本身的直径比对照侧大约 40%。根据上述术后生存时间，建议保留的 C3 触须柱的发育改变至少有两个阶段。
The development of changes in cortical representation of a C3 mystacial vibrissa in the rat was studied with [14C]2-deoxyglucose (2-DG) autoradiography after neonatal unilateral ablation of all but the C3 whisker follicle. The 2-DG-labeled column, which was produced by stroking the spared C3 vibrissa, was enlarged (35%) at postnatal day (p.d.) 5 and reached 140% by p.d. 12, as compared to the control C3 vibrissa column in the opposite hemisphere. The diameter of the C3 barrel itself on the involved side was about 40% larger than that of the control side at all ages. Based upon the above postoperative survival times, at least two stages in the altered development of the spared C3 vibrissa column are suggested.