Hippocampal sharp-wave ripples in waking and sleeping states.
Hippocampal sharp-wave ripples in waking and sleeping states.
复制标题
海马尖波在清醒和睡眠状态下波动。
DOI：
10.1016/j.conb.2015.05.001
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发表时间：
2015
影响因子：
5.7
通讯作者：
Frank,LorenM
中科院分区：
文献类型：
--
作者：
Roumis,DemetrisK;Frank,LorenM
海马swr包括清醒和睡眠时的神经活动再激活。清醒和睡眠状态下的swr具有不同的特征，特别是回放精度。清醒swr的特征表明它在快速导航规划中起着重要作用。睡眠中swr的特征表明它在逐渐的记忆巩固中起作用。清醒和睡眠状态是不同记忆过程的特殊时期。在清醒的行为中，快速检索先前的经验有助于记忆引导的决策。在睡眠中，一系列逐渐被重新激活的联想支持了事件在记忆网络中的巩固。在清醒和睡眠状态下，海马体位置细胞在被称为锐波波纹的事件中同步爆发，在分布式电路中传递相关的神经模式。睡眠和清醒时的锐波涟漪之间的差异，特别是再现经验的准确性，突出了它们在记忆过程中的状态依赖作用。
HighlightsHippocampal SWRs contain neural activity reactivations in both waking and sleeping.SWRs in waking and sleeping entail distinct features, particularly replay accuracy.Features of awake SWRs suggest a role in rapid navigational planning.Features of sleep SWRs suggest a role in gradual memory consolidation.Waking and sleeping states are privileged periods for distinct mnemonic processes. In waking behavior, rapid retrieval of previous experience aids memory-guided decision making. In sleep, a gradual series of reactivated associations supports consolidation of episodes into memory networks. Synchronized bursts of hippocampal place cells during events called sharp-wave ripples communicate associated neural patterns across distributed circuits in both waking and sleeping states. Differences between sleep and awake sharp-wave ripples, and in particular the accuracy of recapitulated experience, highlight their state-dependent roles in memory processes.