The stiffness of human cataract lenses is a function of both age and the type of cataract
The stiffness of human cataract lenses is a function of both age and the type of cataract
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DOI：
10.1016/j.exer.2007.12.009
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发表时间：
2008-04-01
影响因子：
3.4
通讯作者：
Truscott, Roger J. W.
中科院分区：
文献类型：
--
作者：
Heys, Karl R.;Truscott, Roger J. W.
手术证据表明，核性白内障晶状体通常比正常晶状体更硬。我们使用动态力学分析对手术中摘除的白内障晶状体进行了定量研究，并将结果与正常晶状体的数据进行了比较。硬度的tens中心被发现取决于白内障的类型和患者的年龄。核性白内障晶状体通常比从主要为皮质性白内障的患者中取出的晶状体更硬，后一组中的一些晶状体似乎与年龄匹配的正常人没有显著差异。在40-50岁时，发现晚期核性白内障晶状体的核区域比同龄正常晶状体的核区域硬约46倍。到70-80岁时，晚期核性白内障晶状体的硬度增加了一倍，然而，到这个年龄时，正常晶状体的硬度也显著增加，使得白内障晶状体和正常晶状体之间的差异不太明显，大约为2.5倍。(C)2008爱思唯尔有限公司保留所有权利。
Surgical evidence suggests that nuclear cataract lenses are generally harder than normal lenses. We examined this quantitatively using dynamic mechanical analysis of cataract lenses removed during surgery and compared the results with data from normal lenses. Stiffness of the tens centre was found to depend on the type of cataract and the age of the patient. Nuclear cataract lenses were generally stiffer than those extracted from patients with predominantly cortical cataract, with some in the latter group appearing not to differ significantly from age-matched normals. At age 40-50, the nuclear region of advanced nuclear cataract lenses was found to be approximately 46 times harder than that of normal lenses of the same age. By age 70-80 the stiffness of advanced nuclear cataract lenses had doubled, however, by this age, normal lenses had also increased significantly in stiffness so that the difference between cataract and normal lenses was much less pronounced, being a factor of approximately 2.5. (C) 2008 Elsevier Ltd. All rights reserved.