Fearful faces selectively increase corticospinal motor tract excitability: A transcranial magnetic stimulation study
Fearful faces selectively increase corticospinal motor tract excitability: A transcranial magnetic stimulation study
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DOI：
10.1111/j.1469-8986.2007.00635.x
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发表时间：
2008-05-01
期刊：
影响因子：
3.7
通讯作者：
Van Honk, Jack
中科院分区：
文献类型：
--
作者：
Schutter, Dennis J. L. G.;Hofman, Dennis;Van Honk, Jack
恐惧的面部表情是危险信号，会迅速触发一系列与行动准备相关的神经生物学过程。然而，缺乏直接证据证明恐惧的面部表情对运动系统有激活作用。目前的经颅磁刺激（TMS）研究调查了恐惧的面部表情是否选择性地增加皮质脊髓运动束（CST）的兴奋性。 12 名健康的右手志愿者在暴露恐惧、快乐和中性的面部表情时，将局灶性 TMS 应用于左侧初级运动皮层。使用运动诱发电位 (MEP) 记录 CST 兴奋性的变化。结果显示，MEP 对恐惧的面部表情有显着的选择性增加。这些发现为 CST 对威胁的兴奋性选择性增加提供了第一个直接证据，并有助于形成关于情绪和行动准备的进化观点。
Fearful facial expressions are danger signals that rapidly trigger a cascade of neurobiological processes defensibly associated with action preparation. However, direct evidence for the activating effects of fearful facial expressions on the motor system is absent. The current transcranial magnetic stimulation (TMS) study investigated whether fearful facial expressions selectively increase corticospinal motor tract (CST) excitability. Focal TMS was applied over the left primary motor cortex during the exposure of fearful, happy, and neutral facial expressions in 12 healthy right-handed volunteers. Changes in CST excitability using the motor evoked potential (MEP) were recorded. Results showed significant selective increases in MEP to fearful facial expressions. These findings provide the first direct evidence for selective increases in CST excitability to threat and contribute to evolutionary views on emotion and action preparedness.